Sharon Elizabeth Clarke

Dr. Sharon Elizabeth Clarke

orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 September 2019 in IEEE Transactions on Medical Imaging
Verified
Journal Article
Open access
AMAllister Mason
Allister Mason
JRJames Rioux
James Rioux
SCSharon Elizabeth Clarke
Sharon Elizabeth Clarke
ACAndreu Costa
Andreu Costa
MSMatthias Schmidt
Matthias Schmidt
SBSteven Beyea
Steven Beyea
Image quality metrics (IQMs) such as root mean square error (RMSE) and structural similarity index (SSIM) are commonly used in the evaluation and optimization of accelerated magnetic resonance imaging (MRI) acquisition and reconstruction strategies. However, it is unknown how well these indices relate to a radiologist’s perception of diagnostic image quality. In this study, we compare the image quality scores of five radiologists with the RMSE, SSIM, and other potentially useful IQMs: peak signal to noise ratio (PSNR) multi-scale SSIM (MSSSIM), information-weighted SSIM (IWSSIM), gradient magnitude similarity deviation (GMSD), feature similarity index (FSIM), high dynamic range visible difference predictor (HDRVDP), noise quality metric (NQM), and visual information fidelity (VIF). The comparison uses a database of MR images of the brain and abdomen that have been retrospectively degraded by noise, blurring, undersampling, motion, and wavelet compression for a total of 414 degraded images. A total of 1017 subjective scores were assigned by five radiologists. IQM performance was measured via the Spearman rank order correlation coefficient (SROCC) and statistically significant differences in the residuals of the IQM scores and radiologists’ scores were tested. When considering SROCC calculated from combining scores from all radiologists across all image types, RMSE and SSIM had lower SROCC than six of the other IQMs included in the study (VIF, FSIM, NQM, GMSD, IWSSIM, and HDRVDP). In no case did SSIM have a higher SROCC or significantly smaller residuals than RMSE. These results should be considered when choosing an IQM in future imaging studies.

17 May 2021 in Canadian Association of Radiologists Journal
Verified
Journal Article
Open access
PDF file
PMPejman Jabehdar Maralani
Pejman Jabehdar Maralani
AKAnish Kapadia
Anish Kapadia
GLGrace Liu
Grace Liu
FMFelipe Moretti
Felipe Moretti
HGHournaz Ghandehari
Hournaz Ghandehari
NSNicola Schieda
Nicola Schieda
The use of magnetic resonance imaging (MRI) during pregnancy is associated with concerns among patients and health professionals with regards to fetal safety. In this work, the Canadian Association of Radiologists (CAR) Working Group on MRI in Pregnancy presents recommendations for the use of MRI in pregnancy, derived from literature review as well as expert panel opinions and discussions. The working group, which consists of academic subspecialty radiologists and obstetrician-gynaecologists, aimed to provide updated, evidence-based recommendations addressing safety domains related to energy deposition, acoustic noise, and gadolinium-based contrast agent use based on magnetic field strength (1.5T and 3T) and trimester scanned, in addition to the effects of sedative use and occupational exposure.

1 February 2021 in Cancers
Verified
Journal Article
Open access
PDF file
Ahmad ChaddadAhmad Chaddad
Ahmad Chaddad
MKMichael Kucharczyk
Michael Kucharczyk
ACAbbas Cheddad
Abbas Cheddad
SCSharon Elizabeth Clarke
Sharon Elizabeth Clarke
LHLama Hassan
Lama Hassan
Tamim NiaziTamim Niazi
Tamim Niazi
The management of prostate cancer (PCa) is dependent on biomarkers of biological aggression. This includes an invasive biopsy to facilitate a histopathological assessment of the tumor’s grade. This review explores the technical processes of applying magnetic resonance imaging based radiomic models to the evaluation of PCa. By exploring how a deep radiomics approach further optimizes the prediction of a PCa’s grade group, it will be clear how this integration of artificial intelligence mitigates existing major technological challenges faced by a traditional radiomic model: image acquisition, small data sets, image processing, labeling/segmentation, informative features, predicting molecular features and incorporating predictive models. Other potential impacts of artificial intelligence on the personalized treatment of PCa will also be discussed. The role of deep radiomics analysis-a deep texture analysis, which extracts features from convolutional neural networks layers, will be highlighted. Existing clinical work and upcoming clinical trials will be reviewed, directing investigators to pertinent future directions in the field. For future progress to result in clinical translation, the field will likely require multi-institutional collaboration in producing prospectively populated and expertly labeled imaging libraries.

1 October 2021 in Computer Methods and Programs in Biomedicine
Verified
Journal Article
Closed access
DHDavid Hoar
David Hoar
PLPeter Q. Lee
Peter Q. Lee
AGAlessandro Guida
Alessandro Guida
SPSteven Patterson
Steven Patterson
CBChris V. Bowen
Chris V. Bowen
SCSharon Elizabeth Clarke
Sharon Elizabeth Clarke

14 March 2022 in Journal of Magnetic Resonance Imaging
Verified
Journal Article
Closed access
EHElyisha Hanniman
Elyisha Hanniman
ACAndreu F. Costa
Andreu F. Costa
CBChris V. Bowen
Chris V. Bowen
MAMohamed Abdolell
Mohamed Abdolell
ASAshley Stueck
Ashley Stueck
SCSharon Elizabeth Clarke
Sharon Elizabeth Clarke

1 July 2019 in Computerized Medical Imaging and Graphics
Verified
Journal Article
Closed access
PLPeter Q. Lee
Peter Q. Lee
AGAlessandro Guida
Alessandro Guida
SPSteve Patterson
Steve Patterson
TTThomas Trappenberg
Thomas Trappenberg
CBChris Bowen
Chris Bowen
SCSharon Elizabeth Clarke
Sharon Elizabeth Clarke