One of the main issues in dentistry and a barrier to offering dental treatment is anxiety. The usage of music is one of the nonmedical ways to reduce anxiety. Binaural beat technology is used as a music treatment technique. The goal of this study wasto determine whether employing binaural beat technology during and after dental appointments can help patients feel less anxiety and pain. In this clinical trial, 80 patients who were candidates for mandibular wisdom tooth surgery (in 2 test and control groups) were examined. In the control group, after the injection of anaesthesia and before surgery, they waited for 10 minutes and during this time no intervention was done. In the test group, thought, after the injection of anaesthesia, the patients were asked to listen to binaural beat music with headphones for 10 minutes. The level of anxiety of the patients before and after the intervention was checked with the Spielberger State-Trait Anxiety Inventory and finally the data were entered into SPSS version 21 software. The score of overt anxiety (P = .524) and covert anxiety (P = .118) before the start of the study was not significant between the 2 groups, but overt anxiety (P = .001) and covert anxiety (P = .000) after the intervention in the test group decreased significantly. The research showed that the use of binaural beat music has significantly reduced the level of overt and covert anxiety in patients and can be used as an alternative nonpharmacologic method to reduce anxiety.

Sjögren's syndrome (SS) is a common systemic autoimmune disease that affects oral health, and consequently oral health-related quality of life (OHRQoL) due to the involvement of exocrine glands. The present study aimed to evaluate the oral health-related quality of life and oral health indicators in patients with SS in comparison with healthy individuals. In the case and control groups (45 patients and 45 healthy individuals), questions about demographic data, other systemic disorders, medications, the years of infection, xerostomia, as well as inquiries about the quality of life (Oral Health Impact Profile-14 - OHIP-14) were asked. The patients were evaluated clinically, and oral health indicators, including the plaque index (PI), the gingival index (GI), the sulcus bleeding index (SBI), and the number of decayed, missing and filled teeth (DMFT) were assessed on the Ramfjord teeth. Unstimulated saliva samples from both groups were obtained and weighed. The data was analyzed using IBM SPSS Statistics for Windows, v. 24.0. Quantitative variables were compared between the case and control groups with the use of the independent t test or their nonparametric equivalent (the Mann-Whitney test). The comparison of the quantitative variables between the study groups showed a statistically significant difference in the OHRQoL scores (p = 0.037) and the unstimulated saliva flow rate (p = 0.002) between the case and control groups. Also, there was a statistically significant difference in the DMFT index between patients with primary and secondary SS in the case group (p = 0.048). The lower OHRQoL of patients with SS requires more attention and follow-up to solve periodontal and dental problems in this group of patients.

Background and purpose: Candida infections have increased significantly in the antimicrobial resistance era, and synthetic antifungal drugs have limitations. The present work aimed to review the antifungal properties of Zataria multiflora ( Z. multiflora) as an herbal remedy. Method: PubMed, Scopus, ScienceDirect, Web of Science, SID, Civilica, and Magiran databases were searched for the antifungal activity on in vitro, in vivo, dental biofilm, and clinical studies of Z. multiflora on Candida species. Results: Overall, 33 articles evaluated the effect of Z. multiflora on Candida species and classified them into four groups, as follows in vitro (23), dental biofilm (6), in vivo (2), and clinical studies (3). All studies considered Z. multiflora effective in reducing or even inhibiting the growth of Candida species. NoMFC significant differences were seen in the effect of Z. multiflora on susceptible Candida compared to the resistant groups of Candida in the studies. It was also influential in inhibiting C. parapsilosis, C. glabrata, C. krusei, C. kefyer, and C. zeylanoides. Conclusion: Considering the side effects and resistance of current antifungal drugs as well as the benefits of using herbal medicines, such as lower cost, less likely to develop drug resistance, the absence of side effects, and toxicity compared with chemical ones, it is possible as a powerful alternative to replace or combine with the current antifungal for Candida infection therapy along with other therapies.

This study aimed to evaluate the cellular toxicity of two newly-released acrylic resins (Futura Gen and GC Reline Hard) in comparison with the conventional heat-cure resin (Meliodent). Sample discs from each acrylic resin were placed in 24-well culture plates along with L929 mouse fibroblast cell line. A mixture of the RPMI 1640 medium, antibiotics and 10% FBS was added to the plates and the specimens were incubated in a CO2 incubator. The amount of light absorption by each plate was determined after 1 hour, 24 hours and 1 week by the MTT assay and ELISA. The cytotoxic effect of the resins was compared among groups using the two-way ANOVA and further paired comparison was performed using the post-hoc Tukey’s test. After 1 hour, Futura Gen displayed a significantly lower level of light absorption in comparison with Meliodent (P=0.03). After 24 hours, GC Reline Hard rendered a significantly lower level of light absorption compared to Meliodent (P=0.02). After one-week of incubation, the mean absorption rates for GC Reline Hard, Meliodent and Futura Gen were relatively similar (P>0.05). The lowest and highest level of cytotoxicity among all resins were observed after one week and 1 hour of immersion in water, respectively. All the tested resins induced some degree of cytotoxicity. Cytotoxicity of Futura Gen, GC Reline Hard and Meliodent resins failed to show any significant reduction from 24 hours to one week. Thus, it is recommended to immerse the dentures in water for 24 hours prior to delivery to the patient.