Nan Li

Prof. Nan Li

Peking University Health Science Center
orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
28 January 2021 in The Journal of Clinical Hypertension
Verified
Journal Article
Open access
PDF file
YLYingying Liu
Yingying Liu
NLNan Li
Nan Li
HAHang An
Hang An
ZLZhiwen Li
Zhiwen Li
LZLe Zhang
Le Zhang
RYRongwei Ye
Rongwei Ye
Studies have shown that maternal blood pressure level is associated with neonatal birthweight, but the results are not exactly consistent. As the most common hypertensive disorders during pregnancy, the mechanism of gestational hypertension and pre‐eclampsia that affect fetal growth remain unclear. Our objective was to examine the association of gestational hypertension and pre‐eclampsia with the risk of low birthweight (LBW) and small‐for‐gestational‐age (SGA). Data were obtained from the China–US Collaborative Project for Neural Tube Defects Prevention, a large population‐based cohort study. We selected participants who were registered in two southern provinces, had exact information on gestational blood pressure and pregnancy outcomes, and were not affected by chronic hypertension. Logistic regression was used to adjust for the effects of the main potential confounders, including age, body mass index, education, occupation, ethnicity, folic acid use, and parity. The overall incidences of LBW and SGA were 2.25% and 5.86%, respectively. The incidences of LBW/SGA were 3.58%/7.58% and 6.02%/10.67% for gestational hypertension and pre‐eclampsia group, relative to 2.11%/5.68% and 2.16%/5.74% for normal group. The adjusted odds ratios associated with gestational hypertension/pre‐eclampsia were 1.77 (95% CI: 1.63, 1.92)/3.01 (95% CI: 2.67, 3.40) for LBW and 1.40 (95% CI: 1.32, 1.48)/2.02 (95% CI: 1.84, 2.22) for SGA, respectively. The early onset of gestational hypertension/pre‐eclampsia appeared to be a relatively more detrimental exposure window for both LBW and SGA. Our results support an association between gestational hypertension or pre‐eclampsia and the increased risk of LBW and SGA.

YJYuhe Jiang
Yuhe Jiang
JWJunbo Wang
Junbo Wang
SWShaowei Wu
Shaowei Wu
NLNan Li
Nan Li
YWYiming Wang
Yiming Wang
Ruimao ZhengRuimao Zheng
Ruimao Zheng
Background: The frequency of take-out food consumption has increased rapidly among Chinese college students, which has contributed to high obesity prevalence. However, the relationships between take-out food consumption, body mass index (BMI), and other individual factors influencing eating behavior among college students are still unclear. This study explored the association of take-out food consumption with gender, BMI, physical activity, preference for high-fat and high-sugar (HFHS) food, major category, and degree level among Chinese college students. Methods: Cross-sectional data were collected from 1220 college students in Beijing, China, regarding information about take-out food consumption, physical activity, and preference for HFHS food using a self-reported questionnaire. The logistic linear regression model was used to analyze the association between take-out food consumption and personal and lifestyle characteristics. Results: Out of 1220 college students, 11.6% of college students were overweight or obese. Among the personal and lifestyle characteristics, high frequency of take-out food consumption was significantly associated with a non-medical major, high preference for HFHS food, degree level, and higher BMI, but not physical activity. Conclusion: Among Chinese college students, consumption of take-out food may be affected by major category, preference for HFHS food, degree level, and BMI. This could provide guidance on restrictions of high take-out food consumption, which contributes to high obesity prevalence and high risk for metabolic diseases.

27 September 2022 in BMJ Open
Verified
Journal Article
Open access
PDF file
HAHang An
Hang An
MJMing Jin
Ming Jin
ZLZhiwen Li
Zhiwen Li
LZLe Zhang
Le Zhang
HLHongtian Li
Hongtian Li
NLNan Li
Nan Li
Objective To investigate the impact of gestational hypertension and pre-eclampsia on preterm birth. Design The data were collected from the China–US Collaborative Project for Neural Tube Defect Prevention; this was a large population-based cohort study. Setting and participants We selected participants registered in two southern provinces, for whom we had exact information on gestational blood pressure and pregnancy outcomes, and who were not affected by chronic hypertension. In total, 200 103 participants were recruited from 1993 to 1995. Outcome measures Preterm birth was defined as a singleton pregnancy and birth before 37 gestational weeks. Results The incidences of gestational hypertension and pre-eclampsia were 5.47% and 5.44%, respectively, for women who gave birth at full term, and 5.63% and 7.33%, respectively, for those who gave birth preterm. After adjusting for potential confounders, the risk ratios (RRs) of preterm birth in women with gestational hypertension and pre-eclampsia were 1.04 (95% CI 0.98 to 1.11) and 1.39 (95% CI 1.25 to 1.55), respectively. The associations were stronger for early-onset (<28 weeks of gestation) gestational hypertension (adjusted RR=2.13, 95% CI 1.71 to 2.65) and pre-eclampsia (adjusted RR=8.47, 95% CI 5.59 to 12.80). Conclusions Pre-eclampsia was associated with a higher risk of preterm birth. The early-onset gestational hypertension and pre-eclampsia were associated with more severe risks than late-onset conditions.

15 February 2018 in Clinical Nutrition
Verified
Journal Article
Closed access
SCSen Chen
Sen Chen
NLNan Li
Nan Li
ZMZuguo Mei
Zuguo Mei
RYRongwei Ye
Rongwei Ye
ZLZhiwen Li
Zhiwen Li
MSMary K. Serdula
Mary K. Serdula

1 November 2015 in Journal Of Hypertension
Verified
Journal Article
Closed access
NLNan Li
Nan Li
ZLZhiwen Li
Zhiwen Li
SCSen Chen
Sen Chen
NYNa Yang
Na Yang
ARAiguo Ren
Aiguo Ren
RYRongwei Ye
Rongwei Ye
Increasing evidence suggest that active smoking is a risk factor for hypertension, but little is known about the effects of passive smoking on this condition. In China, female passive smoking is widespread and severe due to the high proportion of men who smoke, particularly in rural areas. This study assessed whether passive smoking is associated with increased risk of hypertension among nonsmoking women in rural China. A total of 392 nonsmoking women from a rural area of Shanxi Province (northern China) participated in this cross-sectional study. Data on female passive smoking, and other factors known to influence hypertension, were collected during face-to-face interviews. Logistic regression was used to evaluate the association analyses after adjusting for potential confounders. In total, 162 of the 392 participants were hypertensive (41.3%); 118 participants (30.1%) reported exposure to passive smoking, of whom 88.4% were exposed to smoke in the home. After adjusting for age, BMI, education, occupation, drinking status, physical activity, and menopause status, passive smoking conferred an approximately two-fold risk increase of hypertension (adjusted odds ratio = 1.99, 95% confidence interval 1.16, 3.39). The adjusted odds ratios for passive smoking exposure levels of one to three, four to six, and more than six occasions per week were 1.01 (0.39-2.62), 2.57 (1.05-6.30), and 2.59 (1.18-5.69), respectively. In rural areas of northern China, female passive smoking in the home is prevalent. Frequent exposure to secondhand smoke is a risk factor for hypertension among nonsmoking women, which suggests that measures should be taken to prevent passive smoking among this population.

1 August 2017 in The Journal of Pediatrics
Verified
Journal Article
Closed access
NLNan Li
Nan Li
ZLZhiwen Li
Zhiwen Li
RYRongwei Ye
Rongwei Ye
JLJianmeng Liu
Jianmeng Liu
ARAiguo Ren
Aiguo Ren