In this paper, we apply the concept of fractional calculus to study three-dimensional Lotka-Volterra differential equations. We incorporate the Caputo-Fabrizio fractional derivative into this model and investigate the existence of a solution. We discuss the uniqueness of the solution and determine under what conditions the model offers a unique solution. We prove the stability of the nonlinear model and analyse the properties, considering the non-singular kernel of the Caputo-Fabrizio operator. We compare the stability conditions of this system with respect to the Caputo-Fabrizio operator and the Caputo fractional derivative. In addition, we derive a new numerical method based on the Adams-Bashforth scheme. We show that the type of differential operators and the value of orders significantly influence the stability of the Lotka-Volterra system and numerical results demonstrate that different fractional operator derivatives of the nonlinear population model lead to different dynamical behaviors.