Reactive Powder Concrete (RPC) is recognized as a class of ultra-high-performance concrete characterized by a dense microstructure, very low porosity, and superior mechanical properties. Among the key parameters affecting its performance, the curing regime plays a fundamental role in controlling hydration kinetics and strength development. This study experimentally investigates the influence of different thermal curing regimes on the mechanical performance of RPC. Four curing conditions were considered: conventional water curing at 25°C, hot-water curing at 60°C, hot-water curing at 90°C, and steam curing. Standard specimens were tested to determine compressive strength, splitting tensile strength, and modulus of rupture at 7, 28, 56, and 90 days. The experimental results revealed that thermal curing significantly enhances the mechanical properties of RPC compared with conventional curing. Hot-water curing at 60 °C increased compressive strength by approximately 23.4%, 19.4%, 14.9%, and 14.5% at 7, 28, 56, and 90 days, respectively. Similarly, splitting tensile strength improved by about 44–50%, while flexural strength increased by up to 55% compared with the reference mixture. Steam curing achieved the highest compressive strength, reaching 98.2 MPa at 90 days, representing an improvement of approximately 20.8% over normal curing. Although curing at 90°C accelerated early-age strength development, its long-term improvements were lower than those obtained at 60°C, indicating that excessively high temperatures may not provide optimal mechanical efficiency. Overall, the results demonstrate that controlled, moderate thermal curing at approximately 60°C yields the most balanced improvement in RPC mechanical performance, whereas steam curing achieves the highest ultimate compressive strength. The findings highlight the importance of selecting an appropriate curing strategy to optimize the structural performance and efficiency of RPC in advanced concrete applications.