My group studies genetic predisposition to gastrointestinal cancers with a focus on discovery and characterisation of: 1) Genetic variants associated with oesophageal adenocarcinoma and its precursor Barrett’s oesophagus 2) Genetic variants associated with colorectal cancer and its precursor tumours. 3) Genetic variants that are associated with serious adverse events following treatment with chemotherapeutic agents I have led the analysis of genome wide association studies to identify common genetic variants associated with colorectal cancer, Barrett’s oesophagus and toxicity adverse events following treatment with chemotherapeutics used to treat solid tumours.