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Dr. My-Linh Tran
Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST)

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0 Molecular Biology
0 bioactive compounds
0 medicinal plants
0 Secondary metabolite
0 plant genetics

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Journal article
Published: 31 March 2021 in Plants
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Cell and tissue cultures of Catharanthus roseus have been studied extensively as an alternative strategy to improve the production of valuable secondary metabolites. The purpose of this study was to produce C. roseus callus and suspension cell biomass of good quality and quantity to improve the total alkaloids and bis-indole alkaloids. The young stem derived-callus of C. roseus variety Quang Ninh (QN) was grown on MS medium supplemented with 1.5 mg/L 2,4-dichlorophenoxyacetic acid (2,4-D) plus 1.5 mg/L kinetin, and the growth rate increased by 67-fold after 20 days. The optimal conditions for maintaining the cell suspension culture were 150 mg/50 mL cell inoculum, a medium pH of 5.5 and a culture temperature of 25 °C. The low alkaloid content in the culture was compensated for by using endophytic fungi isolated from local C. roseus. Cell extracts of endophytic fungi—identified as Fusarium solani RN1 and Chaetomium funicola RN3—were found to significantly promote alkaloid accumulation. This elicitation also stimulated the accumulation of a tested bis-indole alkaloid, vinblastine. The findings are important for investigating the effects of fungal elicitors on the biosynthesis of vinblastine and vincristine, as well as other terpenoid indole alkaloids (TIAs), in C. roseus QN cell suspension cultures.

ACS Style

Tran Linh; Nguyen Mai; Pham Hoe; Ninh Ngoc; Phan Thao; Ninh Ban; Nguyen Van. Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus. Plants 2021, 10, 672 .

AMA Style

Tran Linh, Nguyen Mai, Pham Hoe, Ninh Ngoc, Phan Thao, Ninh Ban, Nguyen Van. Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus. Plants. 2021; 10 (4):672.

Chicago/Turabian Style

Tran Linh; Nguyen Mai; Pham Hoe; Ninh Ngoc; Phan Thao; Ninh Ban; Nguyen Van. 2021. "Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus." Plants 10, no. 4: 672.

Journal article
Published: 20 June 2020 in Journal of Nanomaterials
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Drought is a major abiotic stress that negatively impacts plant growth and crop production. Among various techniques used to alleviate drought stress in plants, nanoparticle application is considered to be effective and promising. In this study, the responses of plants treated with iron, copper, cobalt, and zinc oxide nanoparticles (NPs) were analyzed in soybean under drought-induced conditions. The obtained results indicated that these metal-based NPs supported the drought tolerance of NP-treated plants. The desired physiological traits, viz., relative water content, drought tolerance index, and biomass reduction rate, were significantly improved, especially in iron NP-treated plants. At the molecular level, quantitative PCR analysis of several drought-responsive genes revealed a gene-, tissue-, and NP-dependent upregulation of gene expression. Iron NP treatment promoted the expression of all tested genes in roots; additionally, the expression of three drought-responsive genes increased in leaves of all NP-treated plants, while the expression of GmERD1 (Early Responsive to Dehydration 1) was induced in both roots and shoots under the four NP treatments tested. Our findings suggest that NP application can improve drought tolerance of soybean plants by triggering drought-associated gene expression.

ACS Style

Tran My Linh; Nguyen Chi Mai; Pham Thi Hoe; Le Quynh Lien; Ninh Khac Ban; Le Thi Thu Hien; Nguyen Hoai Chau; Nguyen Tuong Van. Metal-Based Nanoparticles Enhance Drought Tolerance in Soybean. Journal of Nanomaterials 2020, 2020, 1 -13.

AMA Style

Tran My Linh, Nguyen Chi Mai, Pham Thi Hoe, Le Quynh Lien, Ninh Khac Ban, Le Thi Thu Hien, Nguyen Hoai Chau, Nguyen Tuong Van. Metal-Based Nanoparticles Enhance Drought Tolerance in Soybean. Journal of Nanomaterials. 2020; 2020 ():1-13.

Chicago/Turabian Style

Tran My Linh; Nguyen Chi Mai; Pham Thi Hoe; Le Quynh Lien; Ninh Khac Ban; Le Thi Thu Hien; Nguyen Hoai Chau; Nguyen Tuong Van. 2020. "Metal-Based Nanoparticles Enhance Drought Tolerance in Soybean." Journal of Nanomaterials 2020, no. : 1-13.