Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. Heart failure (HF) occurs when the heart is not able to pump enough blood to satisfy metabolic needs. People diagnosed with chronic HF may suffer from cardiac decompensation events (CDEs), which cause patients’ worsening. Being able to intervene before decompensation occurs is the major challenge addressed in this study. The aim of this study is to exploit available patient data to develop an artificial intelligence (AI) model capable of predicting the risk of CDEs timely and accurately. Materials and Methods: The vital variables of patients (n = 488) diagnosed with chronic heart failure were monitored between 2014 and 2022. Several supervised classification models were trained with these monitoring data to predict CDEs, using clinicians’ annotations as the gold standard. Feature extraction methods were applied to identify significant variables. Results: The XGBoost classifier achieved an AUC of 0.72 in the cross-validation process and 0.69 in the testing set. The most predictive physiological variables for CAE decompensations are weight gain, oxygen saturation in the final days, and heart rate. Additionally, the answers to questionnaires on wellbeing, orthopnoea, and ankles are strongly significant predictors.

The numerous consequences caused by malnutrition in hospitalized patients can worsen their quality of life. The aim of this study was to evaluate the prevalence of malnutrition on the elderly population, especially focusing on women, identify key factors and develop a malnutrition risk predictive model. The study group consisted of 493 older women admitted to the Asunción Klinika Hospital in the Basque Region (Spain). For this purpose, demographic, clinical, laboratory, and admission information was gathered. Correlations and multivariate analyses and the MNA-SF screening test-based risk of malnutrition were performed. Additionally, different predictive models designed using this information were compared. The estimated frequency of malnutrition among this population in the Basque Region (Spain) is 13.8%, while 41.8% is considered at risk of malnutrition, which is increased in women, with up to 16.4% with malnutrition and 47.5% at risk of malnutrition. Sixteen variables were used to develop a predictive model obtaining Area Under the Curve (AUC) values of 0.76. Elderly women assisted at home and with high scores of dependency were identified as a risk group, as well as patients admitted in internal medicine units, and in admissions with high severity.

Background: The emergency department (ED) is often overburdened, due to the high influx of patients and limited availability of attending physicians. This situation highlights the need for improvement in the management of, and assistance provided in the ED. A key point for this purpose is the identification of patients with the highest risk, which can be achieved using machine learning predictive models. The objective of this study is to conduct a systematic review of predictive models used to detect ward admissions from the ED. The main targets of this review are the best predictive algorithms, their predictive capacity, the studies’ quality, and the predictor variables. Methods: This review is based on PRISMA methodology. The information has been searched in PubMed, Scopus and Google Scholar databases. Quality assessment has been performed using the QUIPS tool. Results: Through the advanced search, a total of 367 articles were found, of which 14 were of interest that met the inclusion criteria. Logistic regression is the most used predictive model, achieving AUC values between 0.75–0.92. The two most used variables are the age and ED triage category. Conclusions: artificial intelligence models can contribute to improving the quality of care in the ED and reducing the burden on healthcare systems.

Preventive care and telemedicine are expected to play an important role in reducing the impact of an increasingly aging global population while increasing the number of healthy years. Virtual coaching is a promising research area to support this process. This paper presents a user-centered virtual coach for older adults at home to promote active and healthy aging and independent living. It supports behavior change processes for improving on cognitive, physical, social interaction and nutrition areas using specific, measurable, achievable, relevant, and time-limited (SMART) goal plans, following the I-Change behavioral change model. Older adults select and personalize which goal plans to join from a catalog designed by domain experts. Intervention delivery adapts to user preferences and minimizes intrusiveness in the user’s daily living using a combination of a deterministic algorithm and incremental machine learning model. The home becomes an augmented reality environment, using a combination of projectors, cameras, microphones and support sensors, where common objects are used for projection and sensed. Older adults interact with this virtual coach in their home in a natural way using speech and body gestures on projected user interfaces with common objects at home. This paper presents the concept from the older adult and the caregiver perspectives. Then, it focuses on the older adult view, describing the tools and processes available to foster a positive behavior change process, including a discussion about the limitations of the current implementation.

The population in the world is aging dramatically, and therefore, the economic and social effort required to maintain the quality of life is being increased. Assistive technologies are progressively expanding and present great opportunities; however, given the sensitivity of health issues and the vulnerability of older adults, some considerations need to be considered. This paper presents DigiHEALTH, a suite of digital solutions for long-term healthy and active aging. It is the result of a fruitful trajectory of research in healthy aging where we have understood stakeholders’ needs, defined the main suite properties (that would allow scalability and interoperability with health services), and codesigned a set of digital solutions by applying a continuous reflexive cycle. At the current stage of development, the digital suite presents eight digital solutions to carry out the following: (a) minimize digital barriers for older adults (authentication system based on face recognition and digital voice assistant), (b) facilitate active and healthy living (well-being assessment module, recommendation system, and personalized nutritional system), and (c) mitigate specific impairments (heart failure decompensation, mobility assessment and correction, and orofacial gesture trainer). The suite is available online and it includes specific details in terms of technology readiness level and specific conditions for usage and acquisition. This live website will be continually updated and enriched with more digital solutions and further experiences of collaboration.

Background: Disease trajectories have become increasingly relevant within the context of an aging population and the rising prevalence of chronic illnesses. Understanding the temporal progression of diseases is crucial for enhancing patient care, preventive measures, and effective management. Objective: The objective of this study is to propose and validate a novel methodology for trajectory impact analysis and interactive visualization of disease trajectories over a cohort of 71,849 patients. Methods: This article introduces an innovative comprehensive approach for analysis and interactive visualization of disease trajectories. First, Risk Increase (RI) index is defined that assesses the impact of the initial disease diagnosis on the development of subsequent illnesses. Secondly, visual graphics methods are used to represent cohort trajectories, ensuring a clear and semantically rich presentation that facilitates easy data interpretation. Results: The proposed approach is demonstrated over the disease trajectories of a cohort comprising 71,849 patients from Tolosaldea, Spain. The study finds several clinically relevant trajectories in this cohort, such as that after suffering a cerebral ischemic stroke, the probability of suffering dementia increases 10.77 times. The clinical relevance of the study outcomes have been assessed by an in-depth analysis conducted by expert clinicians. The identified disease trajectories are in agreement with the latest advancements in the field. Conclusion: The proposed approach for trajectory impact analysis and interactive visualization offers valuable graphs for the comprehensive study of disease trajectories for improved clinical decision-making. The simplicity and interpretability of our methods make them valuable approach for healthcare professionals.