Dr. Pettorusso's research activity concerns clinical and preclinical neuropsychopharmacology and the study of the role of numerous neurotransmitter systems in pathological addictions. More recently, he has dedicated himself to the care of some aspects of pharmacovigilance with an interesting scientific production (about 50 publications), and from 2010, he has been the Scientific Responsible of the Regional Center of Information, Training, and Pharmacovigilance of the Villa Maria Pia Clinic.