Evaluation of the presence of symptoms of anxiety and depression in women treated for breast cancer who underwent surgical procedure using one of two alternative methods, either radical mastectomy or breast conserving treatment (BCT). A questionnaire survey involved 85 patients treated in a conservative way and 94 patients after breast amputation. Hospital Anxiety and Depression Scale (HADS), Beck Depression Inventory (BDI) and depression degree evaluation questionnaire were used in the study. The patients' esponses were statistically analyzed. Based on the HADS questionnaire, the total anxiety level in the group of women treated with BCT was 6.96 points, while in the group of patients who had undergone mastectomy the value was 7.8 points. The observed results were statistically significant. In the case of depression, the following values were found: patients after amputation had 8.04 scale value points, and those after BCT had 6.8 scale value points. The observed differences were statistically significant. Negative correlation was found between the level of anxiety and depression. The total level of depression evaluated using the Beck scale was 16.3 points in the BCT group, which means that they suffered from mild depression, while in the mastectomy group the level was 19.6 points, which corresponds to moderate depression. The level of anxiety and depression among women with breast cancer was influenced by the type of the applied surgical procedure and adjuvant chemotherapy. Demographic variables did not influence the level of anxiety and depression.

The growing demand for sustainable and environmentally friendly fuels and the increasing need to diversify energy sources have stimulated significant research in the field of renewable motor fuels. Despite the progress made, there is still a need to expand the feedstocks, optimize technological pathways, and, in particular, conduct comprehensive studies of the compatibility of renewable components with traditional fuels. In light of the above, the authors propose optimizing the properties of renewable fuels by using new vegetable oils and alcohols for their synthesis. The work is focused on studying the basic physical–chemical properties of fatty acid esters and assessing the possibility of using them as renewable components of motor fuels. Renewable components were obtained via the esterification of selected plant oils (rapeseed oil, camelina oil, palm kernel oil, and coconut oil) with different alcohols (ethanol and isobutanol) with further vacuum distillation of esters. The influence of the structure and composition of renewable components on their physical–chemical properties was studied and substantiated. It shows how the carbon number distribution and double bonds in fatty acid radicals influence the properties of renewable components. The paper shows the impact of the type and structure of alcohol used for esterification on the properties of studied products. The regularities in the change in properties of renewable components depending on the composition of oils and alcohols are explained and substantiated from the point of view of physical chemistry and the basics of forces of intermolecular interactions. Renewable components were compared to the properties of conventional motor fuels (diesel fuel and jet fuel). Based on the level of component compatibility with petroleum fuels, recommendations for replacing or blending petroleum fuels with renewable components were proposed.

The study aimed to assess prognostic significance of del(13q14), del(17p13), t(4;14)(p16;q32), and amp(1q21) in newly diagnosed myeloma patients treated mostly with thalidomide-based therapies. All genetic abnormalities except del(13q14) were independent prognostic factors associated with shortened progression-free survival (PFS) and overall survival (OS). Patients with no abnormalities, one abnormality, and ≥2 abnormalities had a median PFS of 41.8, 17.0, and 10.0 months, respectively; a median OS was not reached, 48.0 and 23.3 months, respectively. According to the presence of amp(1q21), t(4;14)(p16;q32), and del(17p13) and the International Staging System (ISS), we stratified patients into low-risk, intermediate-risk and high-risk groups. A median PFS was 52.9, 25.6, and 10.0 months, respectively; a median OS was not reached, 64.0 and 25.0 months, respectively. In conclusion, our study confirmed the prognostic value of cytogenetic changes and showed that prognostic models based on ISS and cytogenetic studies should include not only del(17p13) and t(4;14)(p16;q32), but also amp(1q21).

The construction industry is one of the most hazardous industries, with a high number of working injuries and fatalities. A special issue for occupational accidents in the construction industry is the use of scaffolds, which is usually attributed to falls from height. Research and practice have demonstrated that decisions made upstream from the construction site can influence construction worker safety. Therefore, it is crucial to assess the risk levels for different construction stages on scaffolding, with various work trades, aiming to prevent the occurrence of fall accidents. The use of new techniques and methodologies, such as Building Information Modeling (BIM), is of major importance. The growing implementation of BIM in Architecture, Engineering and Construction (AEC) is changing the way safety can be approached. This study reviews the existing literature about BIM and construction safety on scaffolding, to explore useful findings and detect knowledge gaps for future research. Despite the enormous evolution of research and technological innovations based on BIM for construction safety, there is still a flagrant lack of knowledge and solutions for identifying hazards related to construction on scaffolding.

Problems concerning occupational safety and health are commonly found in the construction industry, including falling materials, tools or people from a height, stepping on objects, and injuries caused by hand tools. An important factor in occupational safety in the construction industry is the use of scaffolds. All scaffolds used in construction, renovation, repair (including isolating, painting and decorating) and demolition, should be erected, maintained and dismantledin accordance with safety procedures. Therefore, it is crucial to deal with the safety of scaffolds and risk assessment in the construction industry; thus, the way of undertaking the assessment and the liability of assessment seems to be essential for professionals. However, it has been found that those professionals are prone to rely heavily on their own experience and knowledge in decision-making regarding risk assessment. The Scaffold Use Risk Assessment Model (SURAM) has been developed for assessing risk levels at various stages of the construction process in various work trades. The SURAM is the result of a research project carried out at 60 construction sites in Poland and Portugal where 504 observations have been completed including both harmful physical and chemical factors, stress level, workers' habits, as well as a hundreds ex-post reconstruction of construction accidents scenarios. It was found that the workers' Health Behaviour Index (HBI) seems to be a more direct predictor for development of the unsafe chain of events leading to an accident than the workload, and concentration of harmful factors at the workplace. The developed HBI module of SURAM seems to be beneficial for predicting high-risk construction activities, and thus preventing the occurrence of accidents, based on a set of historical accident data.

Effect of infliximab on the levels of TNF-alpha and TGF-beta in the whole blood cultures of irradiated patients.