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Dr. Esmaeil Khedmati Morasae
Centre for Circular Economy, Exeter University Business School, University of Exeter, Exeter, UK

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0 Social Epidemiology
0 System Dynamics
0 Systems Thinking
0 Complex systems science (complexity science/theory)
0 Soft system methodologies

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Research article
Published: 01 February 2021 in Journal of Diabetes & Metabolic Disorders
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Evaluating the process of changes in the Metabolic Syndrome (MetS) components over time is one of the ways to study of the MetS natural history. This study aimed to determine the trend of changes in the progression of MetS from its isolated components. This longitudinal study was performed on four follow-up periods of the Tehran Lipid and Glucose Study (TLGS) between 1999 and 2015. The research population consisted of 3905 adults over the age of 18 years. MetS was diagnosed based on the Joint Interim Statement (JIS). The considered components were abdominal obesity, hypertension, hyperglycemia, and dyslipidemia. The highest incidence of MetS from its components was related to hypertension in the short term (3.6-year intervals). In the long run, however, the highest increase in the MetS incidence occurred due to abdominal obesity. Overall, the incidence of MetS increased due to obesity and dyslipidemia, but decreased due to the other factors. Nonetheless, the trend of MetS incidence from all components increased in total. The most common components were dyslipidemia with a decreasing trend and obesity with an increasing trend during the study. The results indicated that obesity and hypertension components played a more important role in the further development of MetS compared to other components in the Iranian adult population. This necessitates careful and serious attention in preventive and control planning.

ACS Style

Davood Khalili; Pezhman Bagheri; Mozhgan Seif; Abbas Rezaianzadeh; Esmaeil Khedmati Morasae; Ehsan Bahramali; Fereidoun Azizi. The dynamics of metabolic syndrome development from its isolated components among Iranian adults: findings from 17 years of the Tehran lipid and glucose study (TLGS). Journal of Diabetes & Metabolic Disorders 2021, 20, 95 -105.

AMA Style

Davood Khalili, Pezhman Bagheri, Mozhgan Seif, Abbas Rezaianzadeh, Esmaeil Khedmati Morasae, Ehsan Bahramali, Fereidoun Azizi. The dynamics of metabolic syndrome development from its isolated components among Iranian adults: findings from 17 years of the Tehran lipid and glucose study (TLGS). Journal of Diabetes & Metabolic Disorders. 2021; 20 (1):95-105.

Chicago/Turabian Style

Davood Khalili; Pezhman Bagheri; Mozhgan Seif; Abbas Rezaianzadeh; Esmaeil Khedmati Morasae; Ehsan Bahramali; Fereidoun Azizi. 2021. "The dynamics of metabolic syndrome development from its isolated components among Iranian adults: findings from 17 years of the Tehran lipid and glucose study (TLGS)." Journal of Diabetes & Metabolic Disorders 20, no. 1: 95-105.

Journal article
Published: 05 December 2020 in Diabetes & Metabolic Syndrome: Clinical Research & Reviews
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Careful evaluation of the progression trend of the metabolic syndrome (MetS) in children and adolescents (C&A) is one of the important methods of studying the natural history of MetS in them. This study was performed to determine the trend of changes in the progression of MetS from its components. This was a longitudinal study which was performed on data from 4 follow-up periods of Tehran Lipid and Glucose Study (TLGS) between 1999 and 2015. The research population consisted of 6-18-year-old children and adolescents creating 3895-person population. The criteria for the diagnosis of MetS was joint interim statement (JIS). The considered components were central adiposity, high blood pressure, insulin resistance, and dyslipidemia. In this study, in the long term, the highest increase in the MetS’ incidence in boys occurred in obesity and in girls in dyslipidemia and in total mode, in obesity. But in the short term (3.6 year follow-up periods) in the first to fourth periods, in total mode, the highest incidence occurred in dyslipidemia, hyperglycemia, dyslipidemia, and obesity. In terms of trend, in total mode, the highest increase in MetS incidence was related to the obesity component. Also, the incidence of MetS from all components was declining in overall mode. Also, the most common components at the beginning and end of the study in all groups were dyslipidemia with a decreasing and obesity with an increasing trend, respectively. It seems that in Iranian C&As, obesity and dyslipidemia components play a more important role in the further development of the MetS than other components. This matter requires careful and serious attention in preventive and control planning.

ACS Style

Pezhman Bagheri; Davood Khalil; Mozhgan Seif; Esmaeil Khedmati Morasae; Ehsan Bahramali; Fereidoun Azizi; Abbas Rezaianzadeh. The dynamics of metabolic syndrome development from its isolated components among iranian children and adolescents: Findings from 17 Years of the Tehran Lipid and Glucose Study (TLGS). Diabetes & Metabolic Syndrome: Clinical Research & Reviews 2020, 15, 99 -108.

AMA Style

Pezhman Bagheri, Davood Khalil, Mozhgan Seif, Esmaeil Khedmati Morasae, Ehsan Bahramali, Fereidoun Azizi, Abbas Rezaianzadeh. The dynamics of metabolic syndrome development from its isolated components among iranian children and adolescents: Findings from 17 Years of the Tehran Lipid and Glucose Study (TLGS). Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2020; 15 (1):99-108.

Chicago/Turabian Style

Pezhman Bagheri; Davood Khalil; Mozhgan Seif; Esmaeil Khedmati Morasae; Ehsan Bahramali; Fereidoun Azizi; Abbas Rezaianzadeh. 2020. "The dynamics of metabolic syndrome development from its isolated components among iranian children and adolescents: Findings from 17 Years of the Tehran Lipid and Glucose Study (TLGS)." Diabetes & Metabolic Syndrome: Clinical Research & Reviews 15, no. 1: 99-108.

Original research paper
Published: 19 May 2020 in Health Expectations
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Introduction There is an extensive literature on public involvement (PI) in research, but this has focused primarily on experiences for researchers and public contributors and factors enabling or restricting successful involvement in specific projects. There has been less consideration of a ‘whole system’ approach to embedding PI across an organization from governance structures through to research projects. Objective To investigate how a combination of two theoretical frameworks, one focused on mainstreaming and the other conceptualizing quality, can illuminate the embedding of positive and influential PI throughout a research organization. Methods The study used data from the evaluation of a large UK research collaboration. Primary data were collected from 131 respondents (including Public Advisers, university, NHS and local government staff) via individual and group interviews/workshops. Secondary sources included monitoring data and internal documents. Findings CLAHRC‐NWC made real progress in mainstreaming PI. An organizational vision and infrastructure to embed PI at all levels were created, and the number and range of opportunities increased; PI roles became more clearly defined and increasingly public contributors felt able to influence decisions. However, the aspiration to mainstream PI throughout the collaboration was not fully achieved: a lack of staff ‘buy‐in’ meant that in some areas, it was not experienced as positively or was absent. Conclusion The two theoretical frameworks brought a novel perspective, facilitating the investigation of the quality of PI in structures and processes across the whole organization. We propose that combining these frameworks can assist the evaluation of PI research.

ACS Style

Fiona Ward; Jennie Popay; Ana Porroche‐Escudero; Dorcas Akeju; Saiqa Ahmed; Jane Cloke; Koser Khan; Shaima Hassan; Esmaeil Khedmati‐Morasae. Mainstreaming public involvement in a complex research collaboration: A theory‐informed evaluation. Health Expectations 2020, 23, 910 -918.

AMA Style

Fiona Ward, Jennie Popay, Ana Porroche‐Escudero, Dorcas Akeju, Saiqa Ahmed, Jane Cloke, Koser Khan, Shaima Hassan, Esmaeil Khedmati‐Morasae. Mainstreaming public involvement in a complex research collaboration: A theory‐informed evaluation. Health Expectations. 2020; 23 (4):910-918.

Chicago/Turabian Style

Fiona Ward; Jennie Popay; Ana Porroche‐Escudero; Dorcas Akeju; Saiqa Ahmed; Jane Cloke; Koser Khan; Shaima Hassan; Esmaeil Khedmati‐Morasae. 2020. "Mainstreaming public involvement in a complex research collaboration: A theory‐informed evaluation." Health Expectations 23, no. 4: 910-918.