Paola Cavalcante obtained her Master’s degree in Biological Sciences, summa cum laude, in 2002 at the Laboratory of Genetics, Cell Biology Department, University of Calabria (Cosenza, Italy) where in 2006 she got her Ph.D. in Molecular Bio-pathology. She joined the UOC Neurologia 4 in 2006 as a post-doc researcher. She has always been actively involved in national and international projects on neuromuscular diseases, particularly myasthenia gravis (MG). Her research activity aims at understanding the immunological alterations underlying these disorders, for the development of more efficient and innovative treatments. Findings from her studies allowed her to disclose a close link between innate immunity and autoimmunity in MG, revealing the contribution of Toll-like receptors (TLRs) and pathogen (e.g. Epstein-Barr virus) infections to the intra-thymic pathogenesis of the disease. In 2013, she was awarded a Grant from the Italian Ministry of Health for a Young Researcher and started to coordinate and work on a project focused on the role of microRNAs as pathogenic factors implicated in MG and potential targets of RNA-based advanced therapies to achieve immunomodulation. Since 2019 she has been in Health Research at the same UOC, where she coordinates a group of junior and senior fellowships working on MG and immune-mediated neurological disorders to improve therapeutic strategies and promote personalized medicine implementation in clinical practice.