Adrian Lussi

Prof. Dr. Adrian Lussi


Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2011 in Caries Research
Verified
Journal Article
Closed access
ALAdrian Lussi
Adrian Lussi
NSN. Schlueter
N. Schlueter
ERE. Rakhmatullina
E. Rakhmatullina
CGC. Ganss
C. Ganss
The quality of dental care and modern achievements in dental science depend strongly on understanding the properties of teeth and the basic principles and mechanisms involved in their interaction with surrounding media. Erosion is a disorder to which such properties as structural features of tooth, physiological properties of saliva, and extrinsic and intrinsic acidic sources and habits contribute, and all must be carefully considered. The degree of saturation in the surrounding solution, which is determined by pH and calcium and phosphate concentrations, is the driving force for dissolution of dental hard tissue. In relation to caries, with the calcium and phosphate concentrations in plaque fluid, the ‘critical pH’ below which enamel dissolves is about 5.5. For erosion, the critical pH is lower in products (e.g. yoghurt) containing more calcium and phosphate than plaque fluid and higher when the concentrations are lower. Dental erosion starts by initial softening of the enamel surface followed by loss of volume with a softened layer persisting at the surface of the remaining tissue. Dentine erosion is not clearly understood, so further in vivo studies, including histopathological aspects, are needed. Clinical reports show that exposure to acids combined with an insufficient salivary flow rate results in enhanced dissolution. The effects of these and other interactions result in a permanent ion/substance exchange and reorganisation within the tooth material or at its interface, thus altering its strength and structure. The rate and severity of erosion are determined by the susceptibility of the dental tissues towards dissolution. Because enamel contains less soluble mineral than dentine, it tends to erode more slowly. The chemical mechanisms of erosion are also summarised in this review. Special attention is given to the microscopic and macroscopic histopathology of erosion.

1 July 2015 in Clinical Oral Investigations
Verified
Journal Article
Closed access
PDF file
TCThiago Saads Carvalho
Thiago Saads Carvalho
PCP. Colon
P. Colon
CGC. Ganss
C. Ganss
MHM. C. Huysmans
M. C. Huysmans
ALAdrian Lussi
Adrian Lussi
AWA. Wiegand
A. Wiegand

1 February 2001 in European Journal of Oral Sciences
Verified
Journal Article
Closed access
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ALAdrian Lussi
Adrian Lussi
BMB. Megert
B. Megert
CLC. Longbottom
C. Longbottom
ERE. Reich
E. Reich
PFP. Francescut
P. Francescut

1 July 2004 in Journal of Dental Research
Verified
Journal Article
Closed access
PDF file
ALAdrian Lussi
Adrian Lussi
RHR. Hibst
R. Hibst
RPR. Paulus
R. Paulus
The onset of caries is characterized by demineralization of dental hard tissues. Optimal fluoridation with respective oral hygiene habits and diet may stop the progression of a lesion and even allow for its remineralization. The aim of modern dentistry must be a preventive approach rather than invasive repair of the disease. This is possible only with early detection and respective preventive measures. Some of today's diagnostic tools are not sensitive enough to detect this early onset of destruction. Tools based on fluorescence could have the possibility to overcome this problem. This overview will focus on today's knowledge of one possible tool, the DIAGNOdent.

29 January 2008 in Clinical Oral Investigations
Verified
Journal Article
Open access
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ALAdrian Lussi
Adrian Lussi
TJT. Jaeggi
T. Jaeggi
Dental erosion is a multifactorial condition: The interplay of chemical, biological and behavioural factors is crucial and helps explain why some individuals exhibit more erosion than others. The erosive potential of erosive agents like acidic drinks or foodstuffs depends on chemical factors, e.g. pH, titratable acidity, mineral content, clearance on tooth surface and on its calcium-chelation properties. Biological factors such as saliva, acquired pellicle, tooth structure and positioning in relation to soft tissues and tongue are related to the pathogenesis of dental erosion. Furthermore, behavioural factors like eating and drinking habits, regular exercise with dehydration and decrease of salivary flow, excessive oral hygiene and, on the other side, an unhealthy lifestyle, e.g. chronic alcoholism, are predisposing factors for dental erosion. There is some evidence that dental erosion is growing steadily. To prevent further progression, it is important to detect this condition as early as possible. Dentists have to know the clinical appearance and possible signs of progression of erosive lesions and their causes such that adequate preventive and, if necessary, therapeutic measures can be initiated. The clinical examination has to be done systematically, and a comprehensive case history should be undertaken such that all risk factors will be revealed.

28 January 2017 in Journal of Oral Rehabilitation
Verified
Journal Article
Closed access
PDF file
TCThiago Saads Carvalho
Thiago Saads Carvalho
ALAdrian Lussi
Adrian Lussi