This study deals with the control of chaotic dynamics of tumor cells, healthy host cells, and effector immune cells in a chaotic Three Dimensional Cancer Model (TDCM) by State Space Exact Linearization (SSEL) technique based on Lie algebra. A non-linear feedback control law is designed which induces a coordinate transformation thereby changing the original chaotic TDCM system into a controlled one linear system. Numerical simulation has been carried using Mathematica that witness the robustness of the technique implemented on the chosen chaotic system.

This paper presents the robust synchronization problem of a 3D chaotic system by using the active control technique. Based on the Gershgorin theorem and Routh-Hurwitz criterion, sufficient algebraic conditions are derived to design a linear controller gain matrix. The conditions are then applied for the robust stability of the synchronization error dynamics in the presence of an unknown bounded smooth external disturbance. The proposed active control strategy with a suitable computation of the linear controller gain matrix is simple in design and establishes fast convergence rates of the synchronization error signals. Numerical simulation results further verified the analytical results.