Digital microfluidic biochips (DMFBs) are attractive instruments for obtaining modern molecular biology and chemical measurements. Due to the increasingly complex measurements carried out on a DMFB, such chips are more prone to failure. To compensate for the shortcomings of the module-based DMFB, this paper proposes a routing-based fault repair method. The routing-based synthesis methodology ensures a much higher chip utilization factor by removing the virtual modules on the chip, as well as removing the extra electrodes needed as guard cells. In this paper, the routing problem is identified as a dynamic path-planning problem and mixed path design problem under certain constraints, and an improved Dijkstra and improved particle swarm optimization (ID-IPSO) algorithm is proposed. By introducing a cost function into the Dijkstra algorithm, the path-planning problem under dynamic obstacles is solved, and the problem of mixed path design is solved by redefining the position and velocity vectors of the particle swarm optimization. The ID-IPSO routing-based fault repair method is applied to a multibody fluid detection experiment. The proposed design method has a stronger optimization ability than the greedy algorithm. The algorithm is applied to $8\times 9$, $8\times 8$, and $7\times 8$ fault-free chips. The proposed ID-IPSO routing-based chip design method saves 13.9%, 14.3%, and 14.5% of the experiment completion time compared with the greedy algorithm. Compared with a modular fault repair method based on the genetic algorithm, the ID-IPSO routing-based fault repair method has greater advantages and can save 39.3% of the completion time on average in the completion of complex experiments. When the ratio of faulty electrodes is less than 12% and 23%, the modular and ID-IPSO routing-based fault repair methods, respectively, can guarantee a 100% failure repair rate. The utilization rate of the electrodes is 18% higher than that of the modular method, and the average electrode usage time is 17%. Therefore, the ID-IPSO routing-based fault repair method can accommodate more faulty electrodes for the same fault repair rate; the experiment completion time is shorter, the average number of electrodes is lower, and the security performance is better.

Smart Campus is an intelligent and smart environment of teaching, learning and living. It is built on the Internet of Things and application services. Colleges and universities are devoted to the construction and development of the smart campus and have completed some digital campuses of different sizes. However, there are still some problems in the current construction and development process, such as low degree of intelligence, free intelligent functions, energy and resource monitoring is still in the traditional mode of non-intelligent management, the functions of terminal application are still simple, can’t keep up with the intelligent development of the campus. In order to help promote the development of smart campus, we designed a database, smart campus mobile terminal APP. The smart campus APP is based on Android system to monitor and control energy and other nodes in the campus. The monitoring method is real-time, clear and efficient. In addition, smart dormitory, smart classroom and smart map function have also been designed to provide a more convenient and safe living environment for teachers and students in our school. And this APP has laid a solid foundation for establishing a smart, efficient, open, harmonious, humane and safe campus.

Digital microfluidic biochips (DMFBs) are increasingly important and are used for point-of-care, drug discovery, clinical diagnosis, immunoassays, etc. Pin-constrained DMFBs are an important part of digital microfluidic biochips, and they have gained increasing attention from researchers. However, many previous works have focused on the problem of electrode addressing and aimed to minimize the number of control pins in pin-constrained DMFBs. Although the number of control pins can be effectively redistributed through broadcast addressing technology, the chip reliability will be reduced if the signals are shared arbitrarily. Arbitrary signal sharing can lead to a large number of actuations for many idle electrodes, and as a result, a trapping charge or decreasing contact angle problem could occur for some electrodes, reducing the reliability of the chip. To address this problem, the appropriate electrode matching object should be carefully selected, and the influence of these factors on chip reliability should be fully considered. For this purpose, we aimed to fully consider electrode addressing and the reliability of the chip in improving the reliability of DMFBs. This paper proposed a pin addressing method based on a support vector machine (SVM) with the reliability constraint algorithm, which can fully consider the electrode addressing method and the reliability of the chip together. The proposed method achieved an average maximum number of electrode actuations that was 53.8% and 18.2% smaller than those of the baseline algorithm and the graph-based algorithm, respectively. The simulation experiment results showed that the proposed method can efficiently solve reliability problems during the DMFB design process.

A design method based on Bayesian decision-making for consider the reliability of digital microfluidic chip was proposed. Simulated results showed the method can achieve shorter assay completion time, high electrode usage rate than other methods.

Component identification and concentration estimation of a gas mixture component are important for gas detection. However, the accuracy of traditional gas identification will decrease if the sample is not balanced or the number of samples is too few. In this paper, a method based on sample expansion is proposed to solve the aforementioned problem. Firstly, the ADASYN-ELM method is proposed to identify the composition of a gas mixture component. The KPCA is used to extract the feature of the sensor signal and the ADASYN method is used to expand the samples. The PSO and GA algorithms were used to optimize the parameters of the ELM classification model to complete the qualitative analysis. Secondly, the S-SMOTE-MLSSVR method was put forward to quantitatively estimate. The S-SMOTE method was used to expand the samples, and the regression model MLSSVR was optimized by PSO and GA algorithms to complete the quantitative analysis. The results show that the accuracy rate after sample expansion is generally higher and the MAPE and RMSE are generally lower than before sample expansion, indicating that the sample expansion method has a positive effect on classification and concentration estimation of mixed gases with extremely unbalanced samples and too few samples.

Proposed Spatial-Temporal Deep Learning Network directly ingests raw DPV signals for end-to-end heavy metal ion (Cd, Pb, Cu) detection. It simultaneously achieves classification and concentration regression, eliminating manual feature engineering.