Seaweeds are a renewable natural source of valuable macro and micronutrients that have attracted the attention of the scientists in the last years. Their medicinal properties were already recognized in the ancient traditional Chinese medicine, but only recently there has been a considerable increase in the study of these organisms in attempts to demonstrate their health benefits. The extraction process and conditions to be used for the obtention of value-added compounds from seaweeds depends mainly on the desired final product. Thermochemical conversion of seaweeds, using high temperatures and solvents (including water), to obtain high-value products with more potential applications continues to be an industrial practice, frequently with adverse impact on the environment and products’ functionality. However more recently, alternative methods and approaches have been suggested, searching not only to improve the process performance, but also to be less harmful for the environment. A biorefinery approach display a valuable idea of solving economic and environmental drawbacks, enabling less residues production close to the much recommended zero waste system. The aim of this work is to report about the new developed methods of seaweeds extractions and the potential application of the components extracted.

Developing efficient and sustainable extraction technologies for valuable biocompounds from seaweed is crucial to overcome the limitations of conventional technologies. This study aims to compare three innovative technologies for agar extraction from two red seaweed species, G. sesquipedale and G. vermiculophylla: subcritical water extraction (performed at 125 °C, 2.5 atm, 1 min, and at 140 °C, 3.8 atm, 1 s), moderate electric fields (applied at 85 °C for 120 min and 95 °C for 180 min), and a combination of both methods. The comparison used life cycle assessment and life cycle costing methodologies, considering a gate-to-gate approach. The combined technology demonstrated the lowest energy consumption, with 67 MJ/kg_agar for G. vermiculophylla and 100 MJ/kg_agar for G. sesquipedale. A carbon footprint reduction of up to 94 % was obtained when compared to the control, with 15.9 kg_{CO2 eq.} /kg_agar for G. vermiculophylla and 20.4 kg_{CO2 eq.} /kg_agar for G. sesquipedale. Using photovoltaic panels as alternative energy further cut carbon emissions by 50 %. The cost analysis showed that the combined technology was the most cost-effective extraction method.