After claiming nearly five hundred thousand lives globally, the COVID-19 pandemic is showing no signs of slowing down. While the UK, USA, Brazil and parts of Asia are bracing themselves for the second wave—or the extension of the first wave—it is imperative to identify the primary social, economic, environmental, demographic, ethnic, cultural and health factors contributing towards COVID-19 infection and mortality numbers to facilitate mitigation and control measures. We process several open-access datasets on US states to create an integrated dataset of potential factors leading to the pandemic spread. We then apply several supervised machine learning approaches to reach a consensus as well as rank the key factors. We carry out regression analysis to pinpoint the key pre-lockdown factors that affect post-lockdown infection and mortality, informing future lockdown-related policy making. Population density, testing numbers and airport traffic emerge as the most discriminatory factors, followed by higher age groups (above 40 and specifically 60+). Post-lockdown infected and death rates are highly influenced by their pre-lockdown counterparts, followed by population density and airport traffic. While healthcare index seems uncorrelated with mortality rate, principal component analysis on the key features show two groups: states (1) forming early epicenters and (2) experiencing strong second wave or peaking late in rate of infection and death. Finally, a small case study on New York City shows that days-to-peak for infection of neighboring boroughs correlate better with inter-zone mobility than the inter-zone distance. States forming the early hotspots are regions with high airport or road traffic resulting in human interaction. US states with high population density and testing tend to exhibit consistently high infected and death numbers. Mortality rate seems to be driven by individual physiology, preexisting condition, age etc., rather than gender, healthcare facility or ethnic predisposition. Finally, policymaking on the timing of lockdowns should primarily consider the pre-lockdown infected numbers along with population density and airport traffic.

There is a concerted effort to develop vaccines to combat the public health crisis caused by COVID-19. Health experts are raising questions concerning the clinical trials, price and distribution of the vaccines among the public. Policymakers must design regulations to allocate vaccines equitably based on epidemiological as well as economic considerations. Allocation strategies must factor in the extent and duration of immunity the vaccines yield from future infections. We present a time-varying linear optimization-based approach, which incorporates epidemiological factors, such as population density, susceptible count and infected ratio as well as transportation costs, to disseminate vaccines among zones. Our approach also employs an update rule on the epidemiological statistics spawning from the SEIRD model to learn the extent of immunity provided by the vaccines. Our experiments are performed on the map of New York State with realistic mobility using spatial and ordinary differential equation-based SEIRD models. We show that the proposed approach allocates vaccines optimally while preventing zones from resource starvation. It adapts its vaccine recommendation to meet the prespecified epidemiological and economic policy requirements of zones, and is highly amenable to accommodate multiple immunity ratios, vaccine types and the time-span of acquired vaccine immunity. Moreover, we demonstrate that one can learn the latent immunity ratios of the vaccines to make more informed recommendations with time. Our ordinary differential equation-based analysis on the real demographic and infection data of New York State show that a small fraction of zones tends to exhibit a high resource demand due to their vulnerability to the pandemic spread. Our vaccine allocation strategy incorporates infection ratio as one of the criteria and is applicable to conceive a drug allocation strategy. The results suggest that incorporating the vulnerability score of zones to the epidemic spread into vaccine allocation may enhance recommendations and aid policy making.

COVID-19 is a global health crisis that has altered human life and still promises to create ripples of death and destruction in its wake. The sea of scientific literature published over a short time-span to understand and mitigate this global phenomenon necessitates concerted efforts to organize our findings and focus on the unexplored facets of the disease. In this work, we applied natural language processing (NLP) based approaches on scientific literature published on COVID-19 to infer significant keywords that have contributed to our social, economic, demographic, psychological, epidemiological, clinical, and medical understanding of this pandemic. We identify key terms appearing in COVID literature that vary in representation when compared to other virus-borne diseases such as MERS, Ebola, and Influenza. We also identify countries, topics, and research articles that demonstrate that the scientific community is still reacting to the short-term threats such as transmissibility, health risks, treatment plans, and public policies, underpinning the need for collective international efforts towards long-term immunization and drug-related challenges. Furthermore, our study highlights several long-term research directions that are urgently needed for COVID-19 such as: global collaboration to create international open-access data repositories, policymaking to curb future outbreaks, psychological repercussions of COVID-19, vaccine development for SARS-CoV-2 variants and their long-term efficacy studies, and mental health issues in both children and elderly.

Unmanned Aerial Vehicles (UAVs), as aerial base stations, is a promising solution for providing end-to-end wireless communications to ground users, thanks to its positioning, flexibility, and autonomy. However, to provide end-to-end wireless communication services, all UAVs must ensure a reliable multi-UAV network topology, even when one or more UAVs are knocked off the network due to hardware/software faults, unreliable wireless connections, etc. Hence, how to design a reliable Multi-UAV network with a minimum number of UAVs becomes a key design issue, which is largely unaddressed in the literature. In this paper, we propose exploring biological robustness to design a reliable MuLtI-UAV NetworK, termed, bio-LINK, which is resilient against the UAV node failures and thus, ensures reliable end-to-end communication services to ground users. We first formulate the above bio-LINK problem as an integer linear programming (ILP) optimization problem and show it is NP-Hard. Next, we propose a polynomial-time heuristic that employs an iterative UAV positioning inspired by Markov Chain Monte Carlo (MCMC) random sampling approach. Our extensive simulation study shows that the proposed algorithm outperforms three baseline algorithms in terms of several considered robustness metrics (e.g., motif count, network efficiency, etc.) and ground user coverage, notwithstanding the random and targeted failure of UAV nodes. When compared with a baseline algorithm with the same number of UAVs, the proposed algorithm retains the motif count by 5-6 folds and improves network efficiency by 39 - 95% and ground user coverage by 2-18%.

Unmanned Aerial Vehicles (UAVs) can be utilized as aerial base stations to establish wireless communication networks in various challenging scenarios, such as emergency disaster areas and rural areas. Under large regions, the aerial communication networks would require UAVs to form wireless (backhaul) links among each other to provide end-to-end wireless services between two or more ground users (via one or more UAVs). Such UAV backhauling in aerial communication networks may be severely compromised if one or more UAVs are knocked off during the time of operation – it may be due to UAV hardware/software faults, limited battery, malicious attacks, etc. Deep reinforcement learning (DRL) has emerged as a powerful tool for learning tasks with large state and continuous action spaces. In this paper, we leverage emerging DRL to achieve reliable backhauling in an aerial communication network that remains functional and supports end-to-end wireless services even under various random and/or targeted UAV node failures. The proposed method (i) maximizes the reliability of UAV backhauling with joint consideration for communication coverage, (ii) learns the complex environment and its dynamics, and (iii) makes 3D positioning decisions for each UAV under the guidance of two deep neural networks. Our performance evaluation reveals that the proposed DRL approach outperforms the baseline method in terms of wireless coverage and network reliability against UAV failures.

Lockdown measures to curb the spread of COVID-19 has brought the world economy on the brink of a recession. It is imperative that nations formulate administrative policies based on the changing economic landscape. In this work, we apply a statistical approach, called topic modeling, on text documents of job loss notices of 26 US states to identify the specific states and industrial sectors affected economically by this ongoing public health crisis. Our analysis reveals that there is a considerable incongruity in job loss patterns between the pre- and during-COVID timelines in several states and the recreational and philanthropic sectors register high job losses. It further shows that the interplay among several possible socioeconomic factors would lead to job losses in many sectors, while also creating new job opportunities in other sectors such as public service, pharmaceuticals and media, making the job loss trends a key indicator of the world economy. Finally, we compare the low income job loss rates against overall job losses due to COVID-19 in the US counties, and discuss the implications of press reports on reopening businesses and the unemployed workforce being absorbed by other sectors.