Hand, foot, and mouth disease (HFMD) is an epidemic infectious disease in China. Its incidence is affected by a variety of natural environmental and socioeconomic factors, and its transmission has strong seasonal and spatial heterogeneity. To quantify the spatial relationship between the incidence of HFMD (I-HFMD) and eight potential risk factors (temperature, humidity, precipitation, wind speed, air pressure, altitude, child population density, and per capita GDP) on the Chinese mainland, we established a geographically weighted regression (GWR) model to analyze their impacts in different seasons and provinces. The GWR model successfully describes the spatial changes of the influence of potential risks, and shows greatly improved estimation performance compared with the ordinary linear regression (OLR) method. Our findings help to understand the seasonally and spatially relevant effects of natural environmental and socioeconomic factors on the I-HFMD, and can provide information to be used to develop effective prevention strategies against HFMD at different locations and in different seasons.

The COVID-19 pandemic has had a profound impact on people’s lives, making accurate prediction of epidemic trends a central focus in COVID-19 research. This study innovatively utilizes a spatiotemporal heterogeneity analysis (GTNNWR) model to predict COVID-19 deaths, simulate pandemic prevention scenarios, and quantitatively assess their preventive effects. The results show that the GTNNWR model exhibits superior predictive capacity to the conventional infectious disease dynamics model (SEIR model), which is approximately 9% higher, and reflects the spatial and temporal heterogeneity well. In scenario simulations, this study established five scenarios for epidemic prevention measures, and the results indicate that masks are the most influential single preventive measure, reducing deaths by 5.38%, followed by vaccination at 3.59%, and social distancing mandates at 2.69%. However, implementing single stringent preventive measures does not guarantee effectiveness across all states and months, such as California in January 2025, Florida in August 2024, and March–April 2024 in the continental U.S. On the other hand, the combined implementation of preventive measures proves 5 to-10-fold more effective than any single stringent measure, reducing deaths by 27.2%. The deaths under combined implementation measures never exceed that of standard preventive measures in any month. The research found that the combined implementation of measures in mask wearing, vaccination, and social distancing during winter can reduce the deaths by approximately 45%, which is approximately 1.5–3-fold higher than in the other seasons. This study provides valuable insights for COVID-19 epidemic prevention and control in America.

The progression of the COVID-19 pandemic has demonstrated significant oscillatory characteristics, underscoring the importance of investigating the impact of driving factors on its evolution. This study included an in-depth analysis of the influence of various driving factors on the pandemic’s fluctuations, identifying key elements, to enhance the comprehension of transmission mechanisms and improve scientific precision in formulating mitigation strategies. The experimental outcomes indicate that the Geographically and Temporally Neural Network Weighted Regression (GTNNWR) model achieved commendable accuracy with minimal error in forecasting the number of infected individuals. Leveraging the results from the GTNNWR model, the research meticulously examines the temporal and spatial correlations between the driving factors and the pandemic, delineated the spatiotemporal distribution patterns of each factor’s influence, and quantified their significance. This study reveals the substantial impact of vaccines, masks, and social distancing measures across different regions and periods, with their effects on the number of affected individuals being 2 to 10 times more pronounced than other driving factors. These findings contribute to a deeper understanding of the spatiotemporal transmission dynamics and the influence of driving factors in the COVID-19 pandemic, offering critical decision-making support for control and prevention efforts.

Duckweed/algal bloom-type black–odorous waters (DAWs) exhibit composite optical properties of vegetation and pollution, posing intractable remote sensing identification challenges in complex environments. Current methods suffer from three critical limitations: a misclassification rate exceeding 25% due to spectral confusion with artificial green covers, an 18.7% false-negative rate for small patches (stemming from the imbalance between CNNs and Transformers), and insufficient feature dimensionality to characterize the dual properties of DAWs. To address these gaps, this study proposes a novel method that integrates the ASGICTVS feature set with a customized SwinTf-Unet model. The ASGICTVS feature set combines vegetation-sensitive metrics, optical water quality indicators, and visual features. The SwinTf-Unet model utilizes an optimized 4 × 4 window, an embedded feature fusion module, and an adaptive shifted window stride to balance global context capture and local detail reconstruction. Experiments on 21,104 GF-2 satellite samples demonstrate that the method achieves 87.50% precision, 88.41% recall, an 85.32% F1-score, and an 83.46% Intersection over Union (IoU), outperforming DeepLabV3+ by 14.56 percentage points in the IoU. With an inference time of 0.87 s per 512 × 512-pixel image and a stable performance across cross-regional datasets (IoU: 82.1–85.3%), it exhibits strong efficiency and generalization. This study resolves DAW spectral confusion, enables high-precision segmentation, and establishes a standardized feature threshold system, providing reliable technical support for large-scale automated DAW monitoring and regional water environment management.