Arboviruses such as Chikungunya (CHIKV), Dengue (DENV), and Zika virus (ZIKV) have emerged as a significant public health concern in Mexico. The existing literature lacks evidence regarding the dispersion of arboviruses, thereby limiting public health policy’s ability to integrate the diagnosis, management, and prevention. This study seeks to reveal the clinical symptoms of CHIK, DENV, and ZIKV by age group, region, sex, and time across Mexico. The confirmed cases of CHIKV, DENV, and ZIKV were compiled from January 2012 to March 2020. Demographic characteristics analyzed significant clinical symptoms of confirmed cases. Multinomial logistic regression was used to assess the association between clinical symptoms and geographical regions. Females and individuals aged 15 and older had higher rates of reported significant symptoms across all three arboviruses. DENV showed a temporal variation of symptoms by regions 3 and 5, whereas ZIKV presented temporal variables in regions 2 and 4. This study revealed unique and overlapping symptoms between CHIKV, DENV, and ZIKV. However, the differentiation of CHIKV, DENV, and ZIKV is difficult, and diagnostic facilities are not available in rural areas. There is a need for adequately trained healthcare staff alongside well-equipped lab facilities, including hematological tests and imaging facilities.

El objetivo del estudio es analizar las características demográficas, comorbilidad y condición médica de las personas infectadas y no-infectadas en México. La información de artículos especializados, noticias científicas, reportes de investigación y notas de agencias de noticias es articulada selectivamente para generar hipótesis para el estudio de caso. La selección de estas hipótesis depende en gran medida de la información disponible y el objetivo de la investigación. Los resultados confirman que los hombres mueren más que las mujeres y que las comorbilidades principales de la población son la hipertensión, la obesidad y la diabetes. El análisis confirma que el tabaquismo no es relevante para la admisión en la Unidad de Cuidados Intensivos (UCI), pero es un factor asociado al fallecimiento de los infectados. El embarazo no está asociado a la gravedad de la infección, medida por admisión en la UCI. Finalmente, el análisis también muestra que la infección del virus no es más aguda en la población indígena infectada. El estudio presenta resultados y sugiere una ruta metodológica que pudiera ser útil para la toma de decisiones en materia de salud. Exploraciones en el buscador Google Scholar muestran que el estudio actual es el primer análisis formal de gran escala que utiliza la base de datos de la Secretaría de Salud de México. The objective of the study is to analyze the demographic characteristics, comorbidity, and medical condition of infected and noninfected people in Mexico. Information from specialized articles, scientific news, research reports, and notes from news agencies is selectively articulated to generate hypotheses for the case study. The selection of these hypotheses depends largely on the available information and the research objective. Main results confirm that men die more often than women and that the main comorbidities in the population are hypertension, obesity, and diabetes. The analysis confirms that smoking is not relevant for admission to the Intensive Care Unit (ICU) but is a factor associated with the death of those infected. Pregnancy is not associated with the severity of the infection, as measured by admission to the ICU. Finally, the analysis also shows that the virus infection is not more acute in the infected indigenous population. The study reports findings and suggests a methodological route to obtain the panorama of contagion that may be useful for decision-making on health. Explorations in the Google Scholar search engine show that the current study is the first formal large-scale analysis that uses the database of the Mexican Ministry of Health.