The aim of this in vitro study was to investigate the fracture resistance, fracture failure pattern, and fractography of four types of chairside computer-aided design/computer-aided manufacturing (CAD/CAM) restoration materials in teeth and titanium abutments fabricated using a standardization method. An artificial mandibular left first premolar prepared for all-ceramic crown restoration was scanned. Forty extracted mandibular molars and cylindrical titanium specimens were milled into a standardized shape. A total of eighty CAD/CAM restoration blocks were milled into a crown and twenty pieces of each lithium disilicate (LS), polymer-infiltrated-ceramic-network (PICN), resin nano ceramic (RNC), and zirconia-reinforced lithium silicate (ZLS) materials were used. Crowns were bonded to abutments, and all specimens underwent thermal cycling treatment for 10,000 cycles. Fracture resistance was measured using a universal testing machine and fracture failure patterns were analyzed using optical microscopy and scanning electron microscopy. Statistical differences were analyzed using appropriate ANOVA, Tukey HSD post hoc tests, and independent sample t-tests (α = 0.05). The results indicated that, in both teeth abutments and titanium abutments, the fracture resistances showed significantly the highest values in LS and the second highest in ZLS (p < 0.05). The fracture resistances based on teeth abutments and titanium abutments were significantly different in all the CAD/CAM restoration materials (p < 0.05). There are statistically significant correlations between the types of materials and the types of abutments (p < 0.05). Each of the different materials showed different fracture failure patterns, and there was no noticeable difference in fractographic analysis. Lithium disilicates and zirconia-reinforced lithium silicates exhibited statistically high fracture resistance, indicating their suitability as restoration materials for natural teeth or implant abutments. There were no distinct differences in the fracture pattern based on the restoration and abutment materials showed that the fracture initiated at the groove where the ball indenter was toughed and propagated toward the axial wall.

Dental caries causes tooth defects and clinical treatment is essential. To prevent further damage and protect healthy teeth, appropriate dental material is a need. However, the biocompatibility of dental material is needed to secure the oral environment. For this purpose, biocompatible materials were investigated for incorporated with dental capping material. Among them, nanomaterials are applied to dental materials to enhance their chemical, mechanical, and biological properties. This research aimed to study the physicochemical and mechanical properties and biocompatibility of a recently introduced light-curable mineral trioxide aggregate (MTA)-like material without bisphenol A-glycidyl methacrylate (Bis-GMA). To overcome the compromised mechanical properties in the absence of Bis-GMA, silica nanoparticles were synthesized and blended with a dental polymer for the formation of a nano-network. This material was compared with a conventional light-curable MTA-like material that contains Bis-GMA. Investigation of the physiochemical properties followed ISO 4049. Hydroxyl and calcium ion release from the materials was measured over 21 days. The Vickers hardness test and three-point flexural strength test were used to assess the mechanical properties. Specimens were immersed in solutions that mimicked human body plasma for seven days, and surface characteristics were analyzed. Biological properties were assessed by cytotoxicity and biomineralization tests. There was no significant difference between the tested materials with respect to overall physicochemical properties and released calcium ions. The newly produced material released more calcium ions on the third day, but 14 days later, the other material containing Bis-GMA released higher levels of calcium ions. The microhardness was reduced in a low pH environment, and differences between the specimens were observed. The flexural strength of the newly developed material was significantly higher, and different surface morphologies were detected. The recently produced extract showed higher cell viability at an extract concentration of 100%, while mineralization was clear at the conventional concentration of 25%. No significant changes in the physical properties between Bis-GMA incorporate material and nanoparticle incorporate materials.

This study investigated the fitting accuracy of titanium alloy fixed dental prostheses (FDP) after sequential CAD/CAM (Computer Aided Design/Computer Aided Manufacturing) fabrication. A three-unit FDP model connecting mandibular second premolars and molars was prepared and scanned to fabricate titanium FDPs by CAD/CAM milling. A total of six FDPs were sequentially milled in one titanium alloy disk using a new set of burs every time (n = 4). The fitting accuracy of FDPs was mesiodistally evaluated by a silicone replica technique and the measurement was triplicated at four different locations: MO (marginal opening), MG (marginal gap), AG (axial gap), and OG (occlusal gap). Data were statistically analyzed using ANOVA and Tukey’s HSD test. The fitting accuracy of PMMA (polymethyl methacrylate) FDPs milled using the worn or new bur were evaluated by the same procedure (n = 6). The mean dimensions of titanium FDP for all measuring positions, except for AG, were significantly increased from the third milling. However, no difference was noted between the first FDP and the second FDP milled with the same set of burs. Severe edge chippings were observed in all milling burs. Detrimental effects of the worn burs on the fitting accuracy were demonstrated in the CAD/CAM-milled PMMA FDP. The results recommend proper changing frequency of cutting burs to achieve the quality of fit and predictable outcomes for dental CAD/CAM prostheses.