Xiaochuan Wang, born in 1970, Professor, doctoral tutor. He is from School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology and was selected in the New Century Excellent Talent Support Program of Ministry of education and became the youth academic leader of the Key Laboratory of Neurological Diseases of the Ministry of Education in 2007. Since 2000, he has been devoted to the basic research of Alzheimer's disease (AD), and has been carried out a series of studies in the etiology, pathogenesis, early diagnosis, animal model establishment and prevention strategies of the AD. He discovered and improved the mechanism of Tau protein degradation and developed neurofibrillary degeneration theory of AD. In addition to, he elucidated the molecular mechanism of the endogenous PP2A inhibitor SET cytoplasm retention and enriched the mechanism of PP2A activity deficiency in AD’s brain. His researches showed that the PP2A activity deficiency may be a triggering factor of AD and amyotrophic lateral sclerosis. His research about screening a number of AD drugs for the corresponding molecular target is also very boutstanding. The Peer-review papers that he has published in Alzheimers & Dementia, PNAS, Acta Neuropathol, Med Res Rev, FASEB J, J Neurosci, JBC, Journal of Alzheimer Disease, etc international influential publications as the correspondence author or co-author is more than 80.