Fast independent component analysis (FastICA) algorithm separates the independent sources from their mixtures by measuring non-Gaussian. FastICA is a common offline method to identify artifact and interference from their mixtures such as electroencephalogram (EEG), magnetoencephalography (MEG), and electrocardiogram (ECG). Therefore, it is valuable to implement FastICA for real-time signal processing. In this paper, the FastICA algorithm is implemented in a field-programmable gate array (FPGA), with the ability of real-time sequential mixed signals processing by the proposed pipelined FastICA architecture. Moreover, in order to increase the numbers precision, the hardware floating-point (FP) arithmetic units had been carried out in the hardware FastICA. In addition, the proposed pipeline FastICA provides the high sampling rate (192 kHz) capability by hand coding the hardware FastICA in hardware description language (HDL). To verify the features of the proposed hardware FastICA, simulations are first performed, then real-time signal processing experimental results are presented using the fabricated platform. Experimental results demonstrate the effectiveness of the presented hardware FastICA as expected.

Rotating machines such as motors, generate noise at the fundamental frequency and its harmonics. The narrowband active noise control (NANC) algorithm is widely used to cancel such noise. Traditional feedforward NANC systems use non-acoustic sensors to measure rotation speeds, and then a bank of signal generators produce synchronized tonal signals as the reference signals according to the fundamental frequency of the undesired noise. However, the non-acoustic sensors such as encoders usually cost a lot and are not reliable. This study proposes using the feedback ANC structure and incorporates with several adaptive line enhancers (ALEs) to generate the reference signals. Without using non-acoustic sensors, the proposed system only updates the center frequency of the first ALE to track the fundamental frequency change, which greatly reduces complexity of the proposed ANC system. The frequency mismatch (FM) problem is overcome by properly setting the bandwidths of the ALE. Performance were verified by using both simulations and real-time experiments.

Many deep-learning-based seizure detection algorithms have achieved good classification, which usually outperformed traditional machine-learning-based algorithms. However, the hand-engineered features increase the computational complexity and potentially have an ineffectiveness problem for the category. Therefore, this paper proposes a novel end-to-end deep-learning model comprising an inception module and a residual module to analyze the multi-scales of original EEG signals and realize seizure detection without feature extraction. Experiments were conducted and evaluated on the Bonn dataset and the CHB-MIT dataset. In the subject-dependent experiments, our model achieved an average F1-score of 69.34% on the CHB-MIT dataset. In subject-independent experiments, our method achieved an average accuracy of 99.04% on the Bonn dataset and an average F1-score of 37.31% on the CHB-MIT dataset. A series of analyses confirmed that our proposed model has better classification performance and lower computational complexity than existing end-to-end seizure detection models.

Background: Support vector machines (SVMs) based on brain-wise functional connectivity (FC) have been widely adopted for single-subject prediction of patients with schizophrenia, but most of them had small sample size. This study aimed to evaluate the performance of SVMs based on a large single-site dataset and investigate the effects of demographic homogeneity and training sample size on classification accuracy.Methods: The resting functional Magnetic Resonance Imaging (fMRI) dataset comprised 220 patients with schizophrenia and 220 healthy controls. Brain-wise FCs was calculated for each participant and linear SVMs were developed for automatic classification of patients and controls. First, we evaluated the SVMs based on all participants and homogeneous subsamples of men, women, younger (18–30 years), and older (31–50 years) participants by 10-fold nested cross-validation. Then, we hold out a fixed test set of 40 participants (20 patients and 20 controls) and evaluated the SVMs based on incremental training sample sizes (N = 40, 80, …, 400).Results: We found that the SVMs based on all participants had accuracy of 85.05%. The SVMs based on male, female, young, and older participants yielded accuracy of 84.66, 81.56, 80.50, and 86.13%, respectively. Although the SVMs based on older subsamples had better performance than those based on all participants, they generalized poorly to younger participants (77.24%). For incremental training sizes, the classification accuracy increased stepwise from 72.6 to 83.3%, with >80% accuracy achieved with sample size >240.Conclusions: The findings indicate that SVMs based on a large dataset yield high classification accuracy and establish models using a large sample size with heterogeneous properties are recommended for single subject prediction of schizophrenia.