Background: This study aimed to assess the feasibility of conducting a prospective study to evaluate histological changes in skin and muscle tissues after two weeks of balneotherapeutic intervention, as described in Romanian medical regulations. Methods: Thirty-five patients participated in this study, thirty of whom received balneotherapy (a cold mud ointment or a mud pack, or a mud bath, and/or a salted water bath) and five received hydrotherapy (the witness plot). Inclusion and exclusion criteria were applied. Twenty-four hours after discharge, a tegument and muscle biopsy were performed, and fragments were histologically prepared. Results: In the blade evidence analysis, the increased caliber and number of open capillaries and the presence of angiogenesis vessels were statistically significant (p = 0.001 < α = 0.05) for the cold mud ointment and mud pack compared with the witness and mud bath plots. The number of angiogenesis blood vessels was higher in the dermis (p < 0.05 *) with the mud pack plot and in the muscle with the mud cold ointment (p < 0.05). The histological study showed that two weeks of therapeutic intervention produced evidence-based proof in the dermis and muscle tissues, which was persistent at least twenty-four hours after the completion of the balneal course. The results encourage the team to continue the histological approach using modern techniques.

Introduction: Spine cord injuries are frequent pathology in general population, which cause significant locomotor disabilities. Objective: We wanted to evaluate the clinical benefits of rehabilitation using natural factors (climate, sapropelic mud, salty water of the lake), applied to patients with spine cord injury. Material and method: We studied (retrospective) patients with spine cord injury at first presentation in Techirghiol health resort, hospitalized from June, 1st 2007 to June, 1st, 2008, undergoing specific rehabilitation treatment and evaluated the clinical benefits of balneal treatment. Results: The first traumatic condition was fall down (37%), and the second car accident (14.4%). The most of them (84%) use wheelchair as support of travel and 30% needs accompanying standing. We noticed after the treatment improvement of muscle activity (both: spastic and flaccid) and psychological and muscle relaxation. Conclusions: Adequate administration of natural factors corroborate with progressive intensity of kinetotherapy or hydro-kineto-therapy completed with electrotherapy and massage lead to improvement of scores of patient. Quality of life of patients can increases in many ways: self esteem, interest for treatment, encouraging other patients, implication in family life and finding new means of support for travel and self assistance.

Background: Sapropelic mud from Techirghiol Lake has been used therapeutically under medical supervision for more than 170 years; however, its comprehensive physicochemical characterization under application-relevant conditions remains insufficiently documented. This study aimed to evaluate the physicochemical properties, mineral and organic composition, ion-exchange capacity, and potential therapeutic mechanisms of Techirghiol sapropelic mud. Methods: Mud samples were analyzed using standardized physicochemical and analytical techniques to determine pH, water content, granulometry, mineral composition, organic fraction, and trace elements. Results: The results indicate that Techirghiol mud is a highly hydrated alkaline peloid characterized by a complex mineral–organic system. Major elements included sodium, calcium, and magnesium, while trace elements such as manganese, iron, and zinc were present in relevant concentrations. The organic fraction, composed of humic substances, lipids, and proteins, reflected advanced but incomplete humification processes. Conclusions: The findings demonstrate the complex physicochemical composition of Techirghiol sapropelic mud and provide a scientific basis for further studies regarding its properties and applications.