Debra L. Safer

Dr. Debra L. Safer

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Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2001 in American Journal of Psychiatry
Verified
Journal Article
Closed access
PDF file
DSDebra L. Safer
Debra L. Safer
CTChristy F. Telch
Christy F. Telch
WAW. Stewart Agras
W. Stewart Agras


29 August 2022 in Nature Medicine
Verified
Journal Article
Open access
PDF file
RSRajat S. Shivacharan
Rajat S. Shivacharan
CRCamarin E. Rolle
Camarin E. Rolle
DBDaniel A. N. Barbosa
Daniel A. N. Barbosa
TCTricia N. Cunningham
Tricia N. Cunningham
AFAustin Feng
Austin Feng
CHCasey H. Halpern
Casey H. Halpern
Cravings that precede loss of control (LOC) over food consumption present an opportunity for intervention in patients with the binge eating disorder (BED). In this pilot study, we used responsive deep brain stimulation (DBS) to record nucleus accumbens (NAc) electrophysiology during food cravings preceding LOC eating in two patients with BED and severe obesity (trial registration no. NCT03868670). Increased NAc low-frequency oscillations, prominent during food cravings, were used to guide DBS delivery. Over 6 months, we observed improved self-control of food intake and weight loss. These findings provide early support for restoring inhibitory control with electrophysiologically-guided NAc DBS. Further work with increased sample sizes is required to determine the scalability of this approach.

1 July 2014 in Surgery for Obesity and Related Diseases
Verified
Journal Article
Closed access
ARAthena H. Robinson
Athena H. Robinson
SASarah Adler
Sarah Adler
HSHelen B. Stevens
Helen B. Stevens
ADAlison M. Darcy
Alison M. Darcy
JMJohn M. Morton
John M. Morton
DSDebra L. Safer
Debra L. Safer

13 November 2019 in International Journal of Eating Disorders
Verified
Journal Article
Closed access
PDF file
DSDebra L. Safer
Debra L. Safer
SASarah Adler
Sarah Adler
SSShebani Sethi
Shebani Sethi
JBJason P. Bentley
Jason P. Bentley
HTHannah Toyama
Hannah Toyama
TNThomas Najarian
Thomas Najarian

18 July 2002 in International Journal of Eating Disorders
Verified
Journal Article
Closed access
PDF file
DSDebra L. Safer
Debra L. Safer
TLTeresa J. Lively
Teresa J. Lively
CTChristy F. Telch
Christy F. Telch
WAW. Stewart Agras
W. Stewart Agras