This is an Open Access Article. It is published by Elsevier under the Creative Commons Attribution 3.0 Unported Licence (CC BY). Full details of this licence are available at: http://creativecommons.org/licenses/by/3.0/In view of the warming climate, there is increasing concern about the likelihood of overheating inside UK\ud buildings that are not mechanically cooled. A number of studies are examining this matter, of which the\ud DeDeRHECC project is one. The recent availability of the UKCP09 future climate data projections has\ud acted as a stimulus to such work. This paper illustrates how field measurement, thermal modelling and\ud the generation of current and future typical and extreme weather years, can be used to provide a picture\ud of the resilience of buildings to climate change. The unified framework for assessing both measurements\ud and current and future predictions that is offered by the BSEN15251 thermal comfort standard is a crucial\ud component. The paper focuses on internal temperatures during the day and at night in wards within the\ud tower building at Addenbrooke’s hospital, which has a hybrid ventilation strategy. The maintenance of\ud thermal comfort in such spaces is critically important and installing air-conditioning in response to\ud climate change is expensive and potentially energy intensive. Fans appear to be a simple retrofit measure\ud that may substantially improve the wards’ resilience to climate change even in extreme years. Whilst\ud healthcare provides the back cloth, the methodology developed has a much wider utility for assessing\ud thermal comfort in buildings in the current and future climate of the UK