Dr. Angélica Rueda holds a PhD in Biochemistry and has been a professor in the Department of Biochemistry, Cinvestav, Mexico, since 2008. Dr. Rueda has been a fellow of the American Heart Association. In 2006, she moved to Ana Maria Gómez and Jean Pierre Benitah's lab (at Inserm, in Montpellier, France) to study calcium handling alterations in vascular myocytes of the diabetic (db/db) mouse. Dr. Rueda has authored 44 publications, including 2 book chapters. She has mentored 12 MSc and 5 PhD students. Dr. Rueda is a member of the SNII, Level 2. In 2010, Dr. Rueda received the Jorge Rosenkranz Prize from Roche México (Young Investigator in Diabetes category) for her research on the functional alteration of cardiac RyRs in metabolic syndrome. In 2016, Dr. Rueda received a Fulbright Fellowship. Dr. Rueda’s lab focuses on elucidating how metabolic alterations change the expression (at the gene and protein levels) and in situ activity of RyRs in vascular and cardiac cells. Her laboratory employs molecular biology (real-time qPCR), biochemistry ([3H]-ryanodine binding and enzymatic assays), immunology (Western blotting and immunocytochemistry), and calcium imaging (confocal line-scan) to analyze alterations in RyR expression, subcellular localization, and in situ activity.