Water is an excellent solvent for organic chemistry and microwave heating offers a very efficient way of heating reaction mixtures. In this article, by focusing on the Suzuki reaction, it is shown how these two methods, used alone or together, can impact modern synthetic chemistry, making reactions faster, easier and cleaner.
8 December 2004 in The Journal of Organic Chemistry
Microwave heating greatly accelerates Pd-catalyzed decarboxylative coupling of aromatic acids and aryl iodides, and allows the coupling of benzoic acids with unactivated arenes.