Todor Liana

Mrs. Todor Liana

universitatea oradea
orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 January 2025 in Medicina
Verified
Journal Article
Open access
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LILIANA SACHELARIELILIANA SACHELARIE
LILIANA SACHELARIE
Scrobota IoanaScrobota Ioana
Scrobota Ioana
IRIoana Romanul
Ioana Romanul
RIRaluca Ortensia Cristina Iurcov
Raluca Ortensia Cristina Iurcov
GCGeorgiana Ioana Potra Cicalău
Georgiana Ioana Potra Cicalău
TLTodor Liana
Todor Liana
Background and Objectives: Periodontal inflammation, often linked to oral microbiota dysbiosis dominated by pathogenic bacteria, remains a significant challenge in periodontitis management. Traditional periodontal therapies primarily reduce the bacterial load but fail to restore the microbiota balance. Probiotics offer a promising therapeutic adjunct with their ability to enhance beneficial bacteria. This study investigates the effects of probiotics on the oral microbiota, inflammatory markers (IL-1β, TNF-α), and clinical parameters (gingival index, bleeding index, and periodontal pocket depth). Materials and Methods: In this pilot study, 80 patients with moderate-to-severe periodontitis were assigned to two groups. Group A received standard periodontal therapy (non-surgical periodontal therapy (NSPT)) with probiotic supplementation (Lactobacillus reuteri, 2 × 10⁹ CFU daily for 8 weeks), and Group B received standard treatment with a placebo. Microbiological changes were assessed via quantitative PCR, while inflammatory markers (IL-1β, TNF-α) were analyzed using ELISA. Clinical parameters, including the gingival index (GI), bleeding index (BI), and periodontal pocket depth (PPD), were measured at baseline (T0), 4 weeks (T1), and 8 weeks (T2) using standardized methods. Results: Probiotic therapy (Group A) significantly reduced the pathogenic bacteria and increased the beneficial bacteria levels compared to the placebo (p < 0.01). Inflammatory markers decreased by 37% (IL-1β) and 42% (TNF-α), while clinical parameters improved, with reductions in the gingival and bleeding indices (−1.5, −1.3) and a 2 mm decrease in the periodontal pocket depth (p < 0.01). Conclusions: Probiotics, as an adjunct to periodontal therapy, effectively restore the microbiota balance, reduce inflammation, and improve clinical outcomes in periodontitis.

TITodor Bianca Ioana
Todor Bianca Ioana
Scrobota IoanaScrobota Ioana
Scrobota Ioana
TLTodor Liana
Todor Liana
ALAlexandra Ioana Lucan
Alexandra Ioana Lucan
Ligia VaidaLigia Vaida
Ligia Vaida
Our study is based on the hypothesis that the prevalence of malocclusions in children is higher in the mining areas from North-Western (NW) Romania than in other geographic areas. We also considered that the distribution of the different types of malocclusions can be correlated with environmental factors. Therefore, the main purpose of the current study was to assess the prevalence of malocclusions in children from the mining areas in NW Romania. Another purpose was to establish the influence of certain environmental factors such as gender, geographical area of origin, and ethnicity on the distribution of malocclusions in order to provide an epidemiological reference for the planning of preventive and treatment programs adapted to the particularity of the mining areas. This cross-sectional study was performed in 2015–2016. The study batch consisted of 960 children from the mining areas, aged 7–14 years, in the period of mixed dentition and early permanent dentition. The clinical examination was conducted by a single examiner, an orthodontic specialist (TBI), in order to avoid inter-operator bias. Occlusion was registered according to Bjoerk. Occlusal clinical signs were followed for the determination of malocclusions. Most children had malocclusions (93.5%). The percentage of anomalies was significantly higher in subjects from Rosia Montana, in girls, and in the Romanians. Data showed that Angle Class I was the most prevalent malocclusion (60.21%), followed by crowding (47.5%), midline shift (43.33%), and deep bite (28.65%). The independent association between ethnicity and total malocclusions shows that the Romanian subjects presented a 3.31 higher chance of developing malocclusions than the Romani ones. The presence of malocclusions was independently influenced by all the studied environmental factors, namely gender, geographical area, and ethnicity. Our results could be relevant for oral health policy-making, i.e., planning preventive and treatment measures of malocclusions, adapted to the peculiarity of the studied mining areas.

4 January 2025 in Medicina
Verified
Journal Article
Open access
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LILIANA SACHELARIELILIANA SACHELARIE
LILIANA SACHELARIE
Scrobota IoanaScrobota Ioana
Scrobota Ioana
CFCIOARA FELICIA
CIOARA FELICIA
TGTIMEA CLAUDIA GHITEA
TIMEA CLAUDIA GHITEA
CȘCorina-Laura Ștefănescu
Corina-Laura Ștefănescu
GCGeorgiana Ioana Potra Cicalău
Georgiana Ioana Potra Cicalău
Background and Objectives: Dental implants are a reliable solution for tooth loss; however, systemic conditions like osteoporosis and diabetes, which affect bone quality, healing, and stability, underline the importance of understanding their impact on enhanced outcomes. This study evaluated the comparative effects of osteoporosis and diabetes on dental implant stability over 12 months, utilizing objective implant mobility and stability measures. Materials and Methods: This prospective cohort study involved 50 patients, divided into 21 with type 2 diabetes and 29 with osteoporosis, with implant stability assessed at 6 and 12 months using Osstell ISQ and Periotest M devices and statistical analysis identifying differences between groups and time intervals at a significance level of p < 0.05. Results: At 6 months, the osteoporosis group showed higher initial stability (mean ISQ: 67.04 ± 5.42) compared to the diabetes group (mean ISQ: 62.10 ± 5.46; p = 0.0215)), and by 12 months, both groups showed significant improvements in ISQ scores (osteoporosis: 68.93 ± 4.83; diabetes: 65.79 ± 3.87), with Periotest values indicating more significant reductions in implant mobility, particularly in diabetic patients (osteoporosis: −3.34 ± 1.59; diabetes: −2.81 ± 1.44; p = 0.0001). Conclusions: Osteoporosis and diabetes significantly impact implant stability through distinct osseointegration pathways, emphasizing the need for personalized treatment plans to improve patient outcomes.

19 May 2025 in Healthcare
Verified
Journal Article
Open access
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IOANA LILEIOANA LILE
IOANA LILE
Tareq HajajTareq Hajaj
Tareq Hajaj
Ioana VejaIoana Veja
Ioana Veja
THTiberiu Hosszu
Tiberiu Hosszu
LVLigia Luminita Vaida
Ligia Luminita Vaida
Diana MarianDiana Marian
Diana Marian
Aim: This study evaluated the efficacy of mouthrinses containing natural compounds—specifically, propolis and green tea extracts—in reducing bacterial dental plaque compared to a placebo and a 0.2% chlorhexidine rinse. We hypothesized that these natural compounds would significantly reduce plaque accumulation, with efficacy comparable to chlorhexidine. Objective: The objective was to evaluate the short-term efficacy of two natural mouthrinses—10% propolis and 5% green tea—compared to a placebo and 0.2% chlorhexidine in reducing dental plaque. Trial Design: The trial design was a randomized, placebo-controlled, parallel-group clinical trial with a 1:1:1:1 allocation ratio. Materials and Methods: In a single-blind, randomized, controlled trial, 60 healthy adult volunteers received a professional mechanical plaque removal (PMPR) and were then randomized into four groups (n = 15 each): a propolis mouthwash, a green tea mouthwash, a 0.2% chlorhexidine mouthwash (positive control), and a placebo rinse. The participants rinsed twice daily for four weeks in addition to standard tooth brushing. The plaque levels were assessed using the Silness–Löe plaque index at baseline and after four weeks. The data were analyzed using ANOVA and post hoc tests (α = 0.05). Ethical approval and informed consent were obtained. Results: All groups had similar baseline plaque scores (≈2.5). After four weeks, the propolis and green tea groups showed significant reductions in plaque (mean indices of 1.02 and 1.12, respectively) compared to the placebo group (mean index = 2.01, p < 0.001). The chlorhexidine group achieved a mean plaque index of 0.90. The propolis rinse showed no significant difference from chlorhexidine (p = 0.40), indicating comparable efficacy. The green tea rinse had a slightly higher plaque index than chlorhexidine (p = 0.03). No significant adverse effects were reported. Conclusions: Mouthwashes containing 10% propolis or 5% green tea significantly reduced dental plaque, with propolis demonstrating efficacy comparable to 0.2% chlorhexidine.

14 July 2025 in Children
Verified
Journal Article
Open access
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LTLaria-Maria Trusculescu
Laria-Maria Trusculescu
D(Dana Emanuela T. Pitic (Cot)
Dana Emanuela T. Pitic (Cot)
ASAndreea Sălcudean
Andreea Sălcudean
RPRamona Amina Popovici
Ramona Amina Popovici
Norina Consuela FornaNorina Consuela Forna
Norina Consuela Forna
TLTodor Liana
Todor Liana
Background/Objectives: Dental anxiety in children is a common issue that can hinder the delivery of effective dental care. Traditional approaches to managing this are often insufficient or involve pharmacological interventions. This study shows the potential of virtual reality (VR) to aid in reducing anxiety in children undergoing simple dental procedures. By immersing children in relaxing VR environments (such as beaches, forests, mountains, or underwater scenes with calm music), the objective is to assess VR’s effectiveness in calming pediatrics patients during these procedures. Methods: Children scheduled for minor dental treatments wore a wearable device that monitored pulse, perspiration, and stress levels. Each child’s baseline data was collected without the VR headset, followed by data collection during VR exposure before and during dental procedures. VR scenarios ranged from soothing nature scenes to animated cartoons, designed to foster relaxation. Results: The data collected showed a reduction in physiological indicators of stress, such as lower heart rate and reduced perspiration, when the VR headset was used. Children appeared more relaxed, with a calmer response during the procedure itself, compared to baseline levels without VR. Conclusions: This study provides preliminary evidence supporting VR as an effective tool for reducing anxiety and stress in pediatric dental patients. By offering an engaging, immersive experience, VR can serve as an alternative or complementary approach to traditional anxiety management strategies in pediatric dentistry, potentially improving patient comfort and cooperation during dental procedures. Further research could determine if VR may serve as an alternative to local anesthesia for non-intrusive pediatric dental procedures.

16 September 2022 in Healthcare
Verified
Journal Article
Open access
PDF file
Abel Emanuel MocaAbel Emanuel Moca
Abel Emanuel Moca
Ioan Andrei TigIoan Andrei Tig
Ioan Andrei Tig
GCGabriela Ciavoi
Gabriela Ciavoi
RIRaluca Ortensia Cristina Iurcov
Raluca Ortensia Cristina Iurcov
LȘLucian Roman Șipoș
Lucian Roman Șipoș
TLTodor Liana
Todor Liana
The COVID-19 pandemic affected the daily lives of the global population, not only in terms of social interaction but also in terms of access to medical and dental care. Non-urgent dental treatments could not be continued during the lockdown and only a small number of dental centres addressed patients with dental emergencies. The aim of this study was to evaluate the socio-demographic characteristics (age, gender, and living environment) of the individuals that accessed the dental emergency centre in Oradea (North-West Romania) and the main causes for accessing the dental emergency service among the population of Oradea (North-West Romania), during the COVID-19 lockdown, between March and May 2020 and, furthermore, to compare the results obtained in the lockdown timeframe (March–May 2020), with the results obtained in the corresponding timeframe in the pre-lockdown year (March–May 2019) and post-lockdown year (March–May 2021). The retrospective study was carried out by analysing the medical records of the patients who were treated in the dental emergency service of the Oradea County Emergency Clinical Hospital in the following periods: March–May 2019, March–May 2020, and March–May 2021. Most patients were treated in 2020, during the lockdown (n = 784), predominantly in April (n = 308). Most patients treated in April 2020 were male patients (43.7%, n = 205) and were aged between 30 and 39 years (19.4%, n = 74). The most frequent types of dental emergencies were acute apical periodontitis and acute pulpitis in all the months and years investigated. During the lockdown months of 2020, acute pulpitis was the most frequent type of emergency in March (42.2%, n = 100) and May (45.6%, n = 109), while in April, acute apical periodontitis was the most frequent type of emergency (43.5%, n = 166). The COVID-19 lockdown led to an increase in the number of patients that required emergency treatments and impacted all groups of people investigated.