(1) Background: This study aims to put into evince the relationship between the variability of the reaction time (RT) during repeated testing, expressed through indicators extracted by the Poincaré plot method, and the age of the participants, their self-reported health (SRH), and level of perceived anxiety. (2) Methods: The study was performed using computerized RT testing software. An observational cross-sectional study was performed on a group of 120 subjects (mean age 42.33 ± 21.12 years), sex ratio men to women 1.14:1. Data were processed through descriptive and inferential statistics. The Poincaré plot method was applied in the analysis of the RT series of data, by calculating the indicators SD₁, SD₂, SD₁/SD₂, and area of the fitting ellipse (AFE) (3) Results: We provided evidence of the excellent reliability of the web-based RT serial testing (Cronbach’s Alpha 0.991) with this sample group. Our results showed that age is an important predictor for mean values of RT, while SD₁, SD₂, and AFE indicators are for SRH (p < 0.01). (4) Conclusions: the variability of RT, expressed by the Poincaré plot indicators, reflects the health status rather than the aging of the subjects and is barely influenced by their level of anxiety.

(1) Background: In this research, we aimed to investigate a computational model of repetitive reaction time (RT) and virtual reaction time (VRT) testing. (2) Methods: The study involved 180 subjects (50 men, 130 women, mean age 31.61 ± 13.56 years). The data were statistically analyzed through the coefficient of variation (CV) and the Poincaré plot indicators. (3) Results: We obtained an excellent level of reliability for both sessions of testing and we put into evidence a relationship of association of the RT and VRT with the subjects’ age, which was more pregnant for RT (p < 0.05). For both RT and VRT data series, we determined a consistent closer association between CV and the Poincaré plot descriptors SD₁, SD₂ (SD—standard deviation), and the area of the fitting ellipse (AFE) (p < 0.01). We reported an underestimation of the time interval of 2 s during the VRT session of testing, with an average value of CV of VRT, the equivalent of the Weber fraction, of 15.21 ± 8.82%. (4) Conclusions: The present study provides novel evidence that linear and nonlinear analysis of RT and VRT variability during serial testing bring complementary insights to the understanding of complex neurocognitive processes implied in the task execution.

This study aimed to investigate the acute specific physiological effects of 15 min of whole-body vibration (WBV) exposure at six different types of vibrations on cardiorespiratory function in 26 healthy young subjects (sex ratio, 1:1; mean age, 20.73 years). The protocols included six variants of a combination of mechanical stimuli with different frequencies (15, 25, and 35 Hz) and direction of stimuli (vertical or diagonal). The investigated cardiorespiratory parameters were heart rate (HR), arterial oxygen saturation (SaO₂), respiratory rate (RR), and spirometric indicators: tidal volume (TV), vital capacity (VC), forced vital capacity (FVC), forced expiratory volume at 1 s (FEV₁), and maximum voluntary ventilation for 12 s (MVV). The data series were statistically processed by using descriptive and inferential statistical methods: the Shapiro–Wilk test, the two-way ANOVA with repeated measures, and post hoc analysis. We obtained significantly higher values for HR, TV, VC, FVC, FEV₁, and MVV after the WBV exposure. These parameters are significantly influenced by both the frequency and direction of stimuli, and certain protocols of WBV are noticeable for their distinct effects. Our results offer a new perspective on the possibility of using preferential variants of vibratory stimulation to obtain maximum cardiorespiratory physiological effects.

The aim of this study was to investigate the acute cardiovascular hemodynamic effects of administration of a fixed dose of 130 mg of caffeine versus placebo in a sample of healthy young adults (N = 32, sex ratio 1/1), who were successively placed in four distinct positions (orthostatic before ingestion, orthostatic, supine and Trendelenburg vertical positions, after ingestion) on a gravitational inversion table. The experimental design was a single-center, parallel-group, double-blind, randomized, placebo-controlled clinical trial. Following the descriptive and inferential statistical processing of the data, a statistical significant pattern (p [0.05) of acute postural cardiovascular hemodynamic adaptation of the subjects was revealed, under the influence of caffeine versus placebo ingestion.

"Introduction: Digital transformation has shifted rehabilitation toward hybrid care models where smartphone applications are used as adjunct tools to support monitoring, exercise delivery, engagement, and self-management in physical therapy. Material and method: This systematic review was conducted according to PRISMA 2020 guidelines and included a comprehensive search of PubMed, Scopus, and Web of Science for studies published between 2021 and 2026 using predefined rehabilitation-related keywords. Strict eligibility criteria, structured study selection, and standardized data extraction were applied, and findings were synthesized narratively due to heterogeneity across interventions, populations, and outcomes. Results: The PRISMA-based selection process identified 15 eligible studies from an initial 215 records, encompassing diverse study designs and clinical populations across musculoskeletal, neurological, orthopaedic, rheumatologic, and geriatric rehabilitation. The included studies evaluated smartphone-based interventions, including exercise prescription applications, telerehabilitation platforms, and digital adherence tools, reporting clinical, behavioural, and implementation-related outcomes. Interventions were classified into four categories: exercise prescription applications, telerehabilitation and monitoring systems, behavioural adherence tools, and self- management or educational platforms. Overall, studies reported improvements in physical activity, functional outcomes, pain, and adherence, while neurological and geriatric populations were predominantly evaluated through feasibility and usability outcomes. Discussion: Smartphone-based applications are increasingly integrated as adjunct tools in physical therapy rehabilitation across diverse clinical populations. Their primary benefits relate to improved adherence, engagement, and continuity of care, with the strongest clinical effects reported in musculoskeletal and postoperative rehabilitation, whereas neurological and geriatric applications remain mainly focused on feasibility and usability outcomes. Conclusions: Smartphone-based applications represent a promising adjunct in physical therapy rehabilitation, with effects mainly mediated through behavioural mechanisms that improve adherence, engagement, and continuity of care. Evidence suggests more consistent clinical benefits in musculoskeletal and postoperative populations, whereas neurological and geriatric studies predominantly report feasibility and usability outcomes, reflecting the need for stronger evidence on long-term effectiveness."