The paddy crop is the most essential and consumable agricultural produce. Leaf disease impacts the quality and productivity of paddy crops. Therefore, tackling this issue as early as possible is mandatory to reduce its impact. Consequently, in recent years, deep learning methods have been essential in identifying and classifying leaf disease. Deep learning is used to observe patterns in disease in crop leaves. For instance, organizing a crop’s leaf according to its shape, size, and color is significant. To facilitate farmers, this study proposed a Convolutional Neural Networks-based Deep Learning (CNN-based DL) architecture, including transfer learning (TL) for agricultural research. In this study, different TL architectures, viz. InceptionV3, VGG16, ResNet, SqueezeNet, and VGG19, were considered to carry out disease detection in paddy plants. The approach started with preprocessing the leaf image; afterward, semantic segmentation was used to extract a region of interest. Consequently, TL architectures were tuned with segmented images. Finally, the extra, fully connected layers of the Deep Neural Network (DNN) are used to classify and identify leaf disease. The proposed model was concerned with the biotic diseases of paddy leaves due to fungi and bacteria. The proposed model showed an accuracy rate of 96.4%, better than state-of-the-art models with different variants of TL architectures. After analysis of the outcomes, the study concluded that the anticipated model outperforms other existing models.

Olive milling produces olive oil and different by-products, all of them very rich in different bioactive compounds like the phenolic alcohol hydroxytyrosol. The aim of the present study was to investigate the effects of an olive fruit extract 20% rich in hydroxytyrosol on the molecular mechanisms associated with Alzheimer disease features like Aβ- and tau- induced toxicity, as well as on oxidative stress in Caenorhabditis elegans. Moreover, characterization of the extracts, regarding the profile and content of phenolics, as well as total antioxidant ability, was investigated. The study of lethality, growth, pharyngeal pumping, and longevity in vivo demonstrated the lack of toxicity of the extract. One hundred μg/mL of extract treatment revealed prevention of oxidative stress and a delay in Aβ-induced paralysis related with a lower presence of Aβ aggregates. Indeed, the extract showed the ability to avoid a certain degree of proteotoxicity associated with aggregation of the tau protein. According to RNAi tests, SKN-1/NRF2 transcription factor and the overexpression of HSP-16.2 were mechanistically associated in the observed effects.

The COVID-19 pandemic has profoundly affected almost all facets of peoples’ lives, various economic areas and regions of the world. In such a situation implementation of a vaccination can be viewed as essential but its success will be dependent on availability and transparency in the distribution process that will be shared among the stakeholders. Various distributed ledgers (DLTs) such as blockchain provide an open, public, immutable system that has numerous applications due the mentioned abilities. In this paper the authors have proposed a solution based on blockchain to increase the security and transparency in the tracing of COVID-19 vaccination vials. Smart contracts have been developed to monitor the supply, distribution of vaccination vials. The proposed solution will help to generate a tamper-proof and secure environment for the distribution of COVID-19 vaccination vials. Proof of delivery is used as a consensus mechanism for the proposed solution. A feedback feature is also implemented in order to track the vials lot in case of any side effect cause to the patient. The authors have implemented and tested the proposed solution using Ethereum test network, RinkeyBy, MetaMask, one clicks DApp. The proposed solution shows promising results in terms of throughput and scalability.

COVID-19 declared as a pandemic that has a faster rate of infection and has impacted the lives and the country’s economy due to forced lockdowns. Its detection using RT-PCR is required long time and due to which its infection has grown exponentially. This creates havoc for the shortage of testing kits in many countries. This work has proposed a new image processing-based technique for the health care systems named “C19D-Net”, to detect “COVID-19” infection from “Chest X-Ray” (XR) images, which can help radiologists to improve their accuracy of detection COVID-19. The proposed system extracts deep learning (DL) features by applying the InceptionV4 architecture and Multiclass SVM classifier to classify and detect COVID-19 infection into four different classes. The dataset of 1900 Chest XR images has been collected from two publicly accessible databases. Images are pre-processed with proper scaling and regular feeding to the proposed model for accuracy attainments. Extensive tests are conducted with the proposed model (“C19D-Net”) and it has succeeded to achieve the highest COVID-19 detection accuracy as 96.24% for 4-classes, 95.51% for three-classes, and 98.1% for two-classes. The proposed method has outperformed well in expressions of “precision”, “accuracy”, “F1-score” and “recall” in comparison with most of the recent previously published methods. As a result, for the present situation of COVID-19, the proposed “C19D-Net” can be employed in places where test kits are in short supply, to help the radiologists to improve their accuracy of detection of COVID-19 patients through XR-Images.

According to the United Nations, the Sustainable Development Goal ‘6’ seeks to ensure the availability and sustainable management of water for all. Digital technologies, such as big data, Internet of Things (IoT), and machine learning (ML) have a significant role and capability to meet the goal. Water quality analysis in any region is critical to identify and understand the standard of water quality and the quality of water is analyzed based on water quality parameters (WQP). Currently, water pollution and the scarcity of water are two major concerns in the region of Uttarakhand, and the analysis of water before it is supplied for human consumption has gained attention. In this study, a big data analytics framework is proposed to analyze the water quality parameters of 13 districts of Uttarakhand and find the correlation among the parameters with the assimilation of IoT and ML. During the analysis, statistical and fractal methods are implemented to understand the anomalies between the water quality parameters in 13 districts of Uttarakhand. The variation in WQP is analyzed using a random forest (RF) model, and the dataset is segmented location wise and the mean, mode, standard deviation, median, kurtosis, and skewness of time series datasets are examined. The mean of the parameters is adjusted with the coefficient of variation based on the standard values of each parameter. The turbidity in almost all the experimental sites has a normal distribution, with the lowest mean value (0.352 mg/L) and highest (11.9 mg/L) in the Pauri Garhwal and Almora districts, respectively. The pH of the water samples is observed to be in the standard range in all the experimental sites, with average and median values being nearly identical, at 7.189 and 7.20, respectively. However, the pH mode is 0.25. The Cl⁻ concentration varies with mean values from the lowest (0.46 mg/L) to the highest (35.2 mg/L) over the experimental sites, i.e., the Bageshwar and Rudraprayag districts, respectively. Based on the analysis, it was concluded that the water samples were found to be safe to drink and in healthy condition in almost all the districts of the state Uttarakhand, except for the Haridwar district, where some increase in contaminants was observed.

MANET is a mobile ad hoc network with many mobile nodes communicating without a centralized module. Infrastructure-less networks make it desirable for many researchers to publish and bind multimedia services. Each node in this infrastructure-less network acts as self-organizing and re-configurable. It allows services to deploy and attain from another node over the ad hoc network. The service composition aims to provide a user’s requirement by combining different atomic services based on non-functional QoS parameters such as reliability, availability, scalability, etc. To provide service composition in MANET is challenging because of the node mobility, link failure, and topology changes, so a traditional protocol will be sufficient to obtain real-time services from mobile nodes. In this paper, the ad hoc on-demand distance vector protocol (AODV) is used and analyzed based on MANET’s QoS (Quality of Service) metrics. The QoS metrics for MANET depends on delay, bandwidth, memory capacity, network load, and packet drop. The requester node and provider node broker acts as a composer for this MANET network. The authors propose a QoS-based Dynamic Secured Broker Selection architecture (QoSDSBS) for service composition in MANET, which uses a dynamic broker and provides a secure path selection based on QoS metrics. The proposed algorithm is simulated using Network Simulator (NS2) with 53 intermediate nodes and 35 mobile nodes of area 1000 m × 1000 m. The comparative results show that the proposed architecture outperforms, with standards, the AODV protocol and affords higher scalability and a reduced network load.