Research activity of Dr. Rosaria Cozzolino is focused on the analysis of Volatile Organic Compounds (VOCs) by Solid Phase Micro-Extraction (SPME) coupled to GC-MS to investigate questions of food and clinical interest. In food flavor analysis, the aim is to develop SPME GC-MS strategies to: (i) Analyze volatile/flavor metabolites to obtain their “profile” in food, often followed by multivariate analysis, used for authenticity testing and product classification and comparison mainly. (ii) Conduct target analysis of compounds that are either restricted, or known as important for quality, processing, and storage. In clinical analysis, the interest is to study the VOCs profiles by SPME GC-MS obtained from biological fluids samples, (i.e., urine), in order to evaluate the potential of the volatile metabolites in the diagnosing and treating of different diseases (autism, diabetes, and obesity).