The Celastraceae family comprises about 96 genera and more than 1.350 species, occurring mainly in tropical and subtropical regions of the world. The species of this family stand out as important plant sources of triterpenes, both in terms of abundance and structural diversity. Triterpenoids found in Celastraceae species display mainly lupane, ursane, oleanane, and friedelane skeletons, exhibiting a wide range of biological activities such as antiviral, antimicrobial, analgesic, anti-inflammatory, and cytotoxic against various tumor cell lines. This review aimed to document all triterpenes isolated from different botanical parts of species of the Celastraceae family covering 2001 to 2021. Furthermore, a compilation of their ¹³C-NMR data was carried out to help characterize compounds in future investigations. A total of 504 pentacyclic triterpenes were compiled and distinguished as 29 aromatic, 50 dimers, 103 friedelanes, 89 lupanes, 102 oleananes, 22 quinonemethides, 88 ursanes and 21 classified as others.

Botanical biopesticides have emerged as sustainable and eco-friendly alternatives to synthetic pesticides, whose indiscriminate use leads to several drawbacks to human and environmental health. To the best of our knowledge, there have been no reports on M. pubescens’ bioactivity on phytopathogens affecting crops as a potential fungicide or antifeedant. This has encouraged us to investigate the potential of the roots of this plant as a source of biopesticides. The present study reports on the evaluation of the roots extract from Magonia pubescens A. St.-Hill., a species from the Cerrado (Brazilian savannah), on the phytopathogenic fungi Botrytis cinerea, Fusarium oxysporum, and Alternaria alternata. In addition, its insect antifeedant effect was assayed against Chrysodeixis chalcites. Thus, an in vitro test-assay was used to determine the fungicide potential (percentage growth inhibition, % GI) of the ethanolic extract of this plant species, whereas a leaf-disk bioassay on the 5th instar larvae of C. chalcites was performed to evaluate its insecticidal potential. The ethanolic extract was further fractionated by liquid–liquid partition using solvents of increasing polarity. The hexane/dichloromethane fraction exhibited a moderated potency and was similar to the ethanolic extract on the three assayed fungi (around % GI 30 at 1 mg/mL), whereas the n-butanol fraction showed a slight improvement of the fungicide effect against B. cinerea (% GI 39.18 at 1 mg/mL). Moreover, the ethanolic extract exhibited a strong antifeedant activity, with a refusal rate (FR) higher than 90% in both choice and non-choice assays against C. chalcites, while the ethyl acetate and n-butanol fractions behaved as appetite suppressors. These results highlight M. pubescens as a promising source of biopesticides and deserve further investigations to optimize extraction procedures.

The increasing social and political pressures related to the environmental problems generated by traditional chemical processes involving the use of toxic solvents, strong acids, and high energy demand suggest utilization of clean methodologies that follow the precepts established by green chemistry. Enzymatic catalysis promotes enantioselective syntheses operating under mild condi-tions of temperature and pressure. The process, however, requires elevated times of reactions and the use of high-cost immobilized derivatives. These consequences usually become obstacles to industrial application of such syntheses. Using of ultrasound and microwaves as alternative heat-ing sources in the enzymatic catalysis, it is possible to overcome these problems besides leading to satisfactory yields and allowing the reduction of solvent volume. In this work, esterification reactions of oleic acid were performed to obtain xylitol monooleate by using alternative method-ologies which agree with the precepts of green chemistry. Yield of 96,5% employing microwave heating and 74,6% with ultrasound were obtained, both using the amount of 2,5 mL of solvent, half of the previous reports. In microwave heating, the reuse of the immobilized enzyme was pos-sible till the third use, retaining yields above 77%. The results showed that was possible to reduce the mass of the catalyst, the volume of the solvent, and the energy consumed in the process with-out significant loss related to the reaction yield.