Dr. Klinge serves as an internationally renowned clinician for diagnosing and neurosurgical treatment of patients with CSF disorders working on the unifying concept of cognitive problems in Hydrocephalus of aging and pediatric patients. Her practice also includes patients with developmental Cerebrospinal fluid disorders, such as Chiari malformation, tethered cord, patients with connective tissue disorders and occult tethered cord syndrome. Her research focuses on the pathophysiology and diagnosis of tethered cord and on establishing criteria for surgical intervention in her practice at Rhode Island Hospital. Dr. Klinge also collaborates with the University of Akron Conquer Chiari Research Center, founded by the Department of Psychology and the Department of Biomedical Engineering on the implications of ageing in Chiari as well as identifying cognitive and imaging biomarkers. Dr. Klinge works on the novel concept of a “Spinal cord motion disorder” that might explain, and support occult neurosurgical pathologies associated with impaired CSF regulation and tethering of the spinal cord. She had been appointed by the National Academy of Sciences and has served in 2022 in a committee to establish disability criteria for the neurological conditions in patients with Ehlers-Danlos-Syndrome and Marfan Syndrome as a nationally acknowledged expert for spinal cord disorders and tethered cord syndrome. Selected Heritable Disorders of Connective Tissue and Disability | National Academies