Adrian Emil Lazarescu

Dr. Adrian Emil Lazarescu

Victor Babes University of Medicine and Pharmacy from Timisoara

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
5 June 2024 in Life
Verified
Journal Article
Open access
PDF file
AFAlexandra Corina Faur
Alexandra Corina Faur
Roxana BuzasRoxana Buzas
Roxana Buzas
ALAdrian Emil Lazarescu
Adrian Emil Lazarescu
LGLaura Andreea Ghenciu
Laura Andreea Ghenciu
Salivary glands tumors are uncommon neoplasms with variable incidence, heterogenous histologies and unpredictable biological behaviour. Most tumors are located in the parotid gland. Benign salivary tumors represent 54–79% of cases and pleomorphic adenoma is frequently diagnosed in this group. Salivary glands malignant tumors that are more commonly diagnosed are adenoid cystic carcinomas and mucoepidermoid carcinomas. Because of their diversity and overlapping features, these tumors require complex methods of evaluation. Diagnostic procedures include imaging techniques combined with clinical examination, fine needle aspiration and histopathological investigation of the excised specimens. This narrative review describes the advances in the diagnosis methods of these unusual tumors—from histomorphology to artificial intelligence algorithms.

28 May 2021 in Medicina
Verified
Journal Article
Open access
PDF file
Gheorghe Bogdan HogeaGheorghe Bogdan Hogea
Gheorghe Bogdan Hogea
JJJenel Marian Pătrașcu Jr.
Jenel Marian Pătrașcu Jr.
ALAdrian Emil Lazarescu
Adrian Emil Lazarescu
LMLouchi El Mehdi
Louchi El Mehdi
ABAndrei Daniel Bolovan
Andrei Daniel Bolovan
JPJenel Marian Patrascu
Jenel Marian Patrascu
Brodie’s abscess is a rare form of sub-acute osteomyelitis that implies the collection of pus inside bone tissue. The present paper presents an extremely rare case of Brodie’s abscess located in the distal femur in a young male patient who refused medical care for three years and presented directly with spontaneous fistula and septic complications. Laboratory tests also suggested chronic septic alterations. Complex imaging investigations including X-ray (RX), computer tomography (CT) and Magnetic Resonance imaging (MRI) confirmed the diagnosis with characteristic aspects, such as the penumbra sign on the T1 weighted MRI image. Management included aggressive debridement, defect reconstruction, and long-term specific antibiotics according to culture harvested intra-operatively. Evolution was positive with inflammatory blood tests returning to physiological values within four weeks and patient full recovery within six months, without any physical deficits. The novelty aspect found in this case presentation is represented by the long-term natural evolution of this pathology, and the fact that even in these conditions, the Brodie’s abscess did not evolve into a ‘malignant’ septic condition, but remained rather benign until the spontaneous fistula prompted the patient to seek medical care.

10 November 2023 in Life
Verified
Journal Article
Open access
PDF file
ABAndrei Daniel Bolovan
Andrei Daniel Bolovan
Roxana Ramona OnofreiRoxana Ramona Onofrei
Roxana Ramona Onofrei
Gheorghe Bogdan HogeaGheorghe Bogdan Hogea
Gheorghe Bogdan Hogea
Ahmed Abu-AwwadAhmed Abu-Awwad
Ahmed Abu-Awwad
ALAdrian Emil Lazarescu
Adrian Emil Lazarescu
Elena AmaricaiElena Amaricai
Elena Amaricai
The management of tibial pilon fractures is challenging and often leads to complications and limitations in ankle function. The study aims to investigate myotonometric parameters and muscle strength of ankle muscles, as well as gait pattern and balance among patients following surgical treatment of pilon fractures. The randomized controlled study will analyze the differences between the patients who will follow a 3-month physical exercise program and will wear customized foot orthoses (i.e., customized orthotic arch support insoles) versus patients who will attend only the physical exercise program. For each group, at least 21 patients will be required. The assessment involves four different testing procedures: myotonometry (anterior tibialis, medial and lateral gastrocnemius, and longus peroneus assessed using MyotonPRO), muscle strength testing (ankle dorsiflexors, plantar flexors, and peroneal muscles assessed using MicroFET2 dynamometer), analysis of gait parameters (using Scheinworks treadmill), and double-leg and single-leg balance tests (using K-Force plate). After 3 months, the assessments will record which of the two treatments (physical exercise program with or without wearing customized foot orthoses) has better outcomes in regaining ankle muscle properties and tone, as well as the restoration of gait and balance.

20 August 2025 in Life
Verified
Journal Article
Open access
PDF file
ABAndrei Daniel Bolovan
Andrei Daniel Bolovan
Gheorghe Bogdan HogeaGheorghe Bogdan Hogea
Gheorghe Bogdan Hogea
Elena AmaricaiElena Amaricai
Elena Amaricai
ATAlexandra-Roxana Tapardea
Alexandra-Roxana Tapardea
ATALINA-DANIELA TOTOREAN
ALINA-DANIELA TOTOREAN
JJJenel Marian Pătrașcu Jr.
Jenel Marian Pătrașcu Jr.
Background: Tibial pilon fractures are usually high-energy fractures that are linked to higher rates of complications and poor clinical outcomes, particularly concerning pain and walking impairments. However, few studies have evaluated postural stability among patients surgically treated for pilon fractures. Objective: This pilot study aimed to evaluate static and dynamic balance in patients who have undergone unilateral pilon fracture fixation, compared to matched healthy controls. Methods: Ten adult patients, post-fixation for unilateral pilon fracture (with clinical and radiological evidence of fracture healing and ability to bear full weight on the affected lower limb), completed a series of balance tests on K-Force plates. Ten matched healthy controls performed the same tests. Outcomes included CoP path length, CoP mean velocity, time to stabilisation (TTS), and peak force normalized to body weight. Results: Patients showed significantly increased mediolateral sway during bipodal stance (mean CoP velocity of 33.7 vs. 22.4 mm/s, p < 0.01), especially under eyes-closed conditions. In single-leg stance, CoP velocity on the affected limb was more than double that of controls (118 vs. 54 mm/s, p = 0.036). Dynamic tests revealed longer TTS after landing (1563 vs. 501 ms, p = 0.048) and lower force output during squats. The unaffected limb performed nearly normally in static tasks but was slower during dynamic stabilization. Conclusions: Even after fracture healing, patients with tibial pilon fractures show persistent sensorimotor deficits and impaired balance.

28 September 2024 in Children
Verified
Journal Article
Open access
PDF file
Marius NegruMarius Negru
Marius Negru
ADANCA RALUCA DINU
ANCA RALUCA DINU
Elena AmaricaiElena Amaricai
Elena Amaricai
LCLiliana Catan
Liliana Catan
ABAndrei Daniel Bolovan
Andrei Daniel Bolovan
Calin PopoiuCalin Popoiu
Calin Popoiu
Background/Objectives: The main aim of our study was to analyze the stabilometric parameters in relation to hip and knee muscle force in children with unilateral slipped capital femoral epiphysis (SCFE) who had undergone surgical treatment. Another objective was to compare the stabilometry in three testing situations (eyes open, eyes closed, and head retroflexed). Methods: In total, 26 patients with unilateral right SCFE treated via in situ fixation with one percutaneous screw performed stabilometry assessments under three different situations (with their eyes open, with their eyes closed, and with their head retroflexed) and isometric muscle force assessment of the bilateral hip flexors, extensors, abductors and adductors and bilateral knee flexors and extensors. Results: No significant differences between the right side (affected hip) and left side (non-affected hip) were recorded for all of the tested muscle groups. We found significant negative correlations between the 90% confidence ellipse area (eyes open condition) and left knee extensors (p = 0.028), right knee flexors (p = 0.041), and left knee flexors (p = 0.02), respectively. When performing the comparison between the eyes open and eyes closed situations, there were significant differences in CoP path length (p < 0.0001) and maximum CoP speed (p = 0.048); the parameters increased in the eyes closed situation. Conclusions: Better postural stability is acquired when assessed with eyes open or with the head retroflexed in contrast with eyes closed testing.

20 April 2024 in Children
Verified
Journal Article
Open access
PDF file
Marius NegruMarius Negru
Marius Negru
ABAndrei Daniel Bolovan
Andrei Daniel Bolovan
Elena AmaricaiElena Amaricai
Elena Amaricai
LCLiliana Catan
Liliana Catan
OBOana Belei
Oana Belei
Calin PopoiuCalin Popoiu
Calin Popoiu
Background: Slipped capital femoral epiphysis (SCFE) is the most common hip disease during infancy and adolescence. Our study aimed to analyze static plantar pressure in children with surgically treated unilateral SCFE. Methods: Twenty-two children with right SCFE with in situ fixation with one percutaneous screw were assessed by PoData plantar pressure analysis under three different conditions (open eyes, eyes closed, and head retroflexed). Results: The total foot loading was significantly higher on the unaffected limb compared with the affected one for all the three testing conditions (p < 0.05). When assessing the differences between testing conditions, there were no significant differences for the right and left foot loadings, or for the three sites of weight distribution, except for the right fifth metatarsal head (lower loading in eyes-closed condition in comparison to eyes open, p = 0.0068), left fifth metatarsal head (increased loading in head-retroflexed condition in comparison to eyes open, p = 0.0209), and left heel (lower loading in head-retroflexed condition in comparison to eyes open, p = 0.0293). Conclusion: Even after a successful surgical procedure, differences in foot loading can impact the postural static activities in different conditions (natural eyes-open, eyes-closed, or head-retroflexed posture).