Prof. Dr. John J. Lemasters is a Professor in the Department of Drug Discovery & Biomedical Sciences, College of Pharmacy, Medical University of South Carolina (MUSC), Charleston, SC, USA. He received his MD and PhD from the Johns Hopkins University School of Medicine in 1975. Prior to joining MUSC, he served as a faculty member at the University of Texas Health Science Center Southwestern Medical School and the University of North Carolina at Chapel Hill. Prof. Lemasters has a long-standing interest in the role of mitochondrial metabolism in hepatopathobiology, especially in relation to ischemia-reperfusion (IR) injury, ethanol/drug-induced hepatic injury, liver preservation for transplantation, cancer, and mitochondrial autophagy (mitophagy).