Hyun Lee, PhD, is a Research Associate Professor in the Department of Pharmaceutical Sciences and the Director of the Biophysics Core at the University of Illinois at Chicago. Dr. Lee has a broad background with compound synthesis, protein-ligand interaction by surface plasmon resonance (SPR) and nuclear magnetic resonance (NMR), protein structure determination by NMR and X-ray crystallography, and enzyme assay development that can benefit drug discovery. She has been focusing on antimicrobial drug development against four flaviviruses (Hepatitis C virus, Zika, Dengue and West Nile viruses) and two coronaviruses (SARS-CoV and MERS-CoV) using various biochemical and biophysical techniques. She has been actively working on developing anti-Tuberculosis drugs recent years. The SPR technique is a powerful tool that can be used in every stage of drug discovery from high-throughput screening (HTS) to hit validation and hit characterization, with which she has extensive knowledge and experience for more than 20 years. She has expertise and experience in compound synthesis, more than 50 different protein purifications, HTS, enzymatic and biophysical assays, structure-activity relationship (SAR) analysis of lead inhibitor candidates, protein-protein/ligand interactions, and structural studies. She has published 60 peer-reviewed publications.