Reported birth prevalences of congenital limb defects (CLD) vary between countries: from 13/10,000 in Finland for the period 1964–1977 to 30.4/10,000 births in Scotland from 1964–1968. Epidemiological studies permit the timely detection of trends in CLD and of associations with other birth defects. The aim of this study is to describe the birth prevalence of CLD in the northern Netherlands.

The present research proposes that empathic concern, as assessed by six items of the ERQ, consists of two separate emotions, i.e., tenderness and sympathy. To test this assumption, nine studies were conducted among, in total, 1,273 participants. In these studies participants were presented with a hypothetical scenario of someone in need, after which empathic concern was assessed. Factor analyses showed that, indeed, the ERQ items that assess empathic concern can be split up in two factors, that is, one reflecting sympathy and one reflecting tenderness. In addition, in line with previous studies, our research showed that, in response to a need-situation that reflects current needs, individuals scored higher on the ERQ factor reflecting sympathy than on the ERQ factor reflecting tenderness. Findings are discussed in terms of the practical and theoretical implications of distinguishing between sympathy and tenderness.

To compare physical activity (PA) in children with juvenile idiopathic arthritis (JIA) with controls and to analyse the effect of disease specific factors on PA in children with JIA treated according to current treatment regimes. PA was measured with a 7-day activity diary and expressed as physical activity level (PAL). Moderate to vigorous physical activity (MVPA) (hours/day) and sedentary time (hours/day) was determined. In children with JIA, medication, the number of swollen and/or painful joints, disease activity, functional ability, pain and well-being was determined. Multivariate regression analysis was performed to analyze differences in PA between JIA and controls, adjusted for influences of age, gender, season, Body Mass Index (BMI) and to analyze predictors of PA in JIA patients. Seventy-six children with JIA (26 boys and 50 girls, mean ± SD age 10.0 ± 1.4 years) and 131 controls (49 boys and 82 girls, mean ± SD age 10.4 ± 1.2 years) participated in this study. Children with JIA had a significantly lower PAL (0.10, p = 0.01) corrected for age, BMI, gender and season. They spent less time in MVPA (0.41 h/day, p = 0.06) and had a significantly higher mean time spent in sedentary activities (0.59 h/day, p 0.02) compared to controls. The activity level of children with JIA was related to age, gender, season, feeling of well-being and pain. Children with JIA have a lower PAL, spent less time in MVPA and spent more time on sedentary activities compared to controls despite current medical treatment and PA encouragement. Data of the children with JIA are from the Rheumates@work study ISRCTN92733069 .