Charlotte leads the projects on the phenomenon of near-death experiences (NDEs) at the GIGA-Consciousness. More generally, Charlotte studies conditions in which people are outwardly unresponsive such as during general anesthesia or cardiac arrest, but ‘disconnected’ or ‘connected’ to the world, as testified by the detailed subjective reports upon awakening. After joining the Centre for Psychedelic Research (Division of Brain Sciences, Imperial College London, UK) in 2019, she has work more extensively on the comparison between (a)typical psychedelic experiences and NDEs, suggesting that the former may model the latter in laboratory settings. To broaden her exploration of human consciousness, she has delved into a comprehensive spectrum of physiological (e.g., hypnosis, cognitive trance), pathological (e.g., disorder of consciousness), and pharmacological (e.g., anesthesia) conditions, demonstrating that unresponsiveness cannot be considered as a surrogate of unconsciousness employing state-of-the-art multimodal functional neuroimaging techniques. Her research is embedded within a unique intellectual framework beyond the classical disciplinary perspectives in science and medicine. She has published more than 100 papers in international peer-reviewed journals such as Nature Reviews Neurology, Trends in Cognitive Sciences, Critical Care and Sciences Advances, and several book chapters. Her contributions have been recognized with awards such as the IBIA Young Investigator Award.