I am an Associate Professor and Chief in the Department of Surgery, Division of Breast Surgery, at City of Hope in Duarte, CA. My research goal is to mitigate breast cancer morbidity and mortality, especially in hormone receptor positive breast cancer (HR+BC), the most common breast cancer subtype. In my clinical practice, I have witnessed time and again progression of HR+BC, despite adherence to treatments such as endocrine therapy. Endocrine therapy, which is universally prescribed as HR+BC treatment, has variable efficacy; a subset of patients with HR+BC will be resistant to this therapy. They often recur early and subsequently die from the disease. To improve the life of my patients and the breast cancer community at-large, my research efforts focus on developing biomarkers to predict efficacy and utility of endocrine therapy toward preventing HR+BC recurrence and death.