I, Jay Kulsh, am a published independent scientist, currently working at University of So. California, though unaffiliated with any of its academic departments. I have been interested in the potential role of enzyme Ribonucleotide Reductase (RnR) in causing cancer ever since I learned about the unique structure of its “free-radical stabilized by two iron atoms” active-site in late 1970’s, as a graduate student in the Department of Chemistry and Biochemistry at University of California, Los Angeles. At that time, based on published Infrared and EPR spectra of the enzyme, I was able to ascertain – first one to do so -- that the free-radical of the active-site is located on phenoxy oxygen of a tyrosine residue. Even when not associated with any research institution or department, I have stayed abreast of growth in knowledge about RnR enzyme, especially as relates to its likely role, vs. role of oncogenes, in carcinogenesis.