Objectives: Public mental health concerns have been raised during the coronavirus disease 2019 (COVID‐19) pandemic. The aim of this study was to assess the psychological impact of the pandemic on dental students in Saudi Arabia.Methods: A cross‐sectional analytical study was conducted among dental students from different universities in Saudi Arabia selected using 2‐stage cluster sampling. The psychological impact was assessed using the validated Arabic version of the Depression, Anxiety and Stress Scale–21 Item questionnaire. The data were analyzed using SPSS software. The Mann–Whitney U and Kruskal–Wallis tests were used as appropriate. A chi‐squared test was used to compare the proportions between the sociodemographic data and logistic regression analysis to identify variables associated with the student's responses.Results: The internal consistency of the scale was excellent (0.954). A total of 697 dental students participated voluntarily in the study; their mean age was 21.76 ± 1.859 years, and 54.7% were female. The majority (96.1%) were single, and 69.4% lived in a household of > 5 persons. Significant differences in mental health outcomes were evident for gender, university, and survey time. Elevated levels of depression, anxiety, and stress were recorded among 60.64%, 37.02%, and 34.92%, respectively, of the students. Females, students who lived alone, and junior students were more likely to experience psychological problems during the COVID‐19 pandemic.Conclusions: The presence of elevated levels of depression, anxiety and stress among dental students highlights the need for psychological empowerment strategies involving institutional counseling services.

A gradual transition from traditional face-to-face learning to online learning has been observed globally following the COVID-19 pandemic. The aim of the study was to compare online and traditional learning methods in relation to orthodontic knowledge and skills acquired in undergraduate courses. A quasi-experimental design was used with two consecutive year classes of 198 dental students at Jazan University, Saudi Arabia. The experimental (virtual) group of 92 students received the content of a clinical orthodontic course virtually using the Blackboard Collaborate™ platform. The control (traditional) group consisted of a previous cohort of 106 students who enrolled in the same course but received traditional classroom education. The students were evaluated through a semester, and both groups obtained the same content and exam questions. The students in the virtual group scored higher in the final theory exam than the traditional group (p-value < 0.05). However, no significant difference in the overall orthodontic knowledge and skills was observed between the groups at the end of the course. Both learning methods showed moderate positive correlation between orthodontic knowledge and skills. In conclusion, virtual learning can serve as an effective alternative to traditional face-to-face learning for teaching orthodontic knowledge and skills to the dental students.

Interleukin-4 (IL-4) is a recognized immunomodulatory cytokine that regulates bone homeostasis. However, the influence of IL-4 on orthodontic tooth movement (OTM) and subsequent root resorption is still unknown. Therefore, the purpose of this study was to investigate the effect of IL-4 on tooth movement and its associated root resorption in a mouse model. The maxillary first molars of four male mice for each experimental group were subjected to mesial force by a nickel titanium coil spring for 12 days. Control mice were not given appliances and injections. Varying doses of IL-4 were injected locally, adjacent to the first molar. Two sets of experiments were designed. The first set was composed of three groups: the control, treatment with phosphate-buffered saline (PBS), or 1.5 µg/day of IL-4. The second set was composed of five groups: the control, treatment with 0 (PBS only), 0.015, 0.15, or 1.5 µg/day of IL-4. The distance of OTM was measured and tartrate-resistant acid phosphatase positive cells along the loaded alveolar bone and root surface were identified. The root resorption associated with OTM was evaluated by a scanning electron microscope. The amount of OTM and the number of osteoclasts were significantly decreased in the IL-4-treated mice. Moreover, IL-4 significantly suppressed force-induced odontoclasts and root resorption. IL-4 inhibits tooth movement and prevents root resorption in the mouse model. These results suggest that IL-4 could be used as a useful adjunct to regulate the extent of OTM and also to control root resorption.

Objectives: Many countries have enforced lockdowns on their populations due to the coronavirus disease 2019 (COVID‐19) pandemic. This study aimed to assess the effects of the lockdown on dental students.Methods: A longitudinal, repeated cross‐sectional study was conducted to evaluate psychological problems experienced by dental students during the COVID‐19 lockdown in Saudi Arabia. The dental students were selected from different universities using 2‐stage cluster sampling. The validated Arabic version of the 21‐item depression, anxiety, and stress scale questionnaire was distributed at the beginning and end of the lockdown. Mann–Whitney U and Kruskal–Wallis tests were used as appropriate. Chi‐square test was used to compare the proportions between the sociodemographic data, and logistic regression analysis was used to identify variables associated with the students’ responses.Results: A total of 1287 respondents participated in this study (695 first‐survey respondents, 592 second‐survey respondents). There were longitudinally significant differences in the students’ mental health outcomes based on gender, university, class year, and survey time during the COVID‐19 lockdown. The lockdown increased the likelihood of female, single, and junior students experiencing stress. The students who lived alone recorded a high chance of elevated levels of depression, anxiety, and stress, which showed a significant longitudinal reduction during the lockdown. Moreover, the lockdown increased the likelihood of mental health problems among the students staying in households of two persons or two‐five persons.Conclusions: This study indicates the importance of considering the detrimental mental health consequences on dental students in the event of future pandemics.