H-BIM paradigms are constituted by 3-D informative contents documenting the current and past state of existing structures. Although the transversal vision and the multidisciplinary interpretation have been attributed to BIM models, in the field of monumental structures, these databases can be organized in different ways depending on the adopted protocol and classifications for the required output of the work. In this manuscript, an H-BIM approach targeted at collecting and providing useful information to execute seismic vulnerability analyses of monumental structures is presented. The BIM modeling followed a protocol based on the following steps: geometrical acquisitions, scan-to-BIM modeling, and informative data collection. The methodology has been applied to the oldest part of Palazzo Vecchio in Florence (IT), an important monumental masonry structure representing the political headquarter of the city since the Middle Ages. The parametric modeling was realized classifying the information according to structural perspectives based on the cognitive steps for the investigation of the existing structures. Finally, a seismic assessment has been realized through a simplified procedure developed for cultural heritage buildings. The outcomes of the evaluation are still part of the collected information of the H-BIM model, as an example of continuous improvement of the available contents of the database.