Background: Numerous free and low-cost mobile apps for the care management of kidney disease have become available in recent years. Although these appear to be promising tools, they have not been evaluated comparatively based on standard mobile app metrics, and thus, limited evidence is available regarding their efficacy. This study systematically cataloged and assessed mobile apps designed to assist medication compliance and nutrition tracking that are useful to the chronic kidney disease (CKD) and the end-stage renal disease (ESRD) patients who are on dialysis. Objective: The objective of this study was to comprehensively evaluate mobile apps used for medication compliance and nutrition tracking for possible use by CKD and ESRD patients. Methods: A systematic review framework was applied to the search, screening, and assessment of apps identified and downloaded from the iOS and Android app stores. We selected apps using 13 relevant search terms, narrowed down based on a set of inclusion and exclusion criteria, and then used the Mobile App Rating Scale (MARS), a widely adopted app evaluation tool to assess the effectiveness of apps. The internal consistency and interrater reliability were tested using Cronbach alpha and interclass correlation coefficients (ICCs), respectively. Results: The MARS total score had excellent internal consistency (Cronbach alpha=.90) and a moderate level of interrater reliability (2-way mixed ICC 0.65). Overall, 11 out of the 12 reviewed apps met the minimum acceptable score of 3.0 in MARS rating. The 3 apps with the highest combined scores were My Kidneys, My Health Handbook (MARS=4.68); My Food Coach (MARS=4.48); and National Kidney Foundation Malaysia (MARS=4.20). The study identified 2 general weaknesses in the existing apps: the apps fell short of accommodating advanced interactive features such as providing motivational feedback and promoting family member and caregiver participations in the app utilization. Conclusions: The MARS rating system performed well in the app evaluation. The 3 highest ranked apps scored consistently high across the 5 dimensions specified in MARS. These apps were developed in collaboration with reputable organizations and field experts, demonstrating the importance of expert guidance in developing medical apps.

Introduction Living-donor kidney transplantation is the gold standard treatment for patients with end-stage kidney disease. However, potential donors ubiquitously face financial as well as logistical barriers. To remove these disincentives from living kidney donations, the governments of 23 countries have implemented reimbursement programmes that shift the burdens of non-medical costs from donors to the governments or private entities. However, scientific evidence for the effectiveness of these programmes is scarce. The present study investigates whether these reimbursement programmes designed to ease the financial and logistical barriers succeeded in increasing the number of living kidney donations at the country level. The study examined within-country variations in the timing of such reimbursement programmes. Method The study applied the difference-in-difference (two-way panel fixed-effect) technique on the Poisson distribution to estimate the effects of these reimbursement programmes on a 17 year long (2000–2016) dataset covering 109 countries where living donor kidney transplants were performed. Results The results indicated that reimbursement programmes have a statistically significant positive effect. Overall, the model predicted that reimbursement programmes increased country-level donation numbers by a factor of 1.12–1.16. Conclusion Reimbursement programmes may be an effective approach to alleviate the kidney shortage worldwide. Further analysis is warranted on the type of reimbursement programmes and the ethical dimension of each type of such programmes.

Understanding the spatial or geographical dependence of income inequality and regional inequality is crucial in the study of inequality. This paper employs a multi-scale, multi-mechanism framework to map and analyze historical patterns of regional and income inequality in the United States (US) by using state and regional panel data spanning over a century. To explore the patterns systematically and see the role of spatial partitioning, we organize the data around several established geographical partitions before conducting various geographical information system (GIS) analyses and statistical techniques. We also investigate the spatial dependence of income inequality and regional inequality. We find that spatial autocorrelation exists for both types of inequality in the US. However, the magnitude of spatial dependence for regional inequality is declining whereas it is volatile for income inequality over time. While income inequality has been at its peak in the most recent decades, we also notice that regional inequality is at its lowest point. As for the choice of partitioning, we observe that within inequality dominates for Census Divisions and Bureau of Economic Analysis (BEA) regions. Conversely, we see that between inequality overall contributes the most to the inequality among Census Regions.

Naoru Koizumi, Abu Bakkar Siddique, Ali Andalibi; Assessment of SARS-CoV-2 Transmission Among Attendees of Live Concert Events in Japan Using Contact Tracing D

The relationship between trade and inequality is complex, and the existing literature concludes that the impacts of trade on inequality are ambiguous. This article addresses this ambiguity and presents robust evidence that the effects of trade on inequality depend on economic development, when it occurred in recent decades, and their various measures. It proposes a novel identification strategy to solve for endogeneity problem in the literature by using trade as predicted by a gravity equation as an instrument for actual trade. It estimates the effect of both trade policies and trade volumes on inequality measured both before and after taxes and transfers. This article takes advantage of large and long panel data by conducting cross-examinations by economic development and economic history. The results show that international trade exacerbates inequality in the pre-taxes, but the effects disappear after taxes and transfers are adjusted; thus, it supports the compensation hypothesis. It increases inequality in rich economies while reducing it in poor economies, which confirms the standard Stolper and Samuelson theorem. Post-1991 trade experience was inequality increasing but pre-1991 trade was inequality decreasing; however, trade opening by reducing regulations, taxes, and tariffs was always inequality increasing. (JEL codes: D63, P33, and F63)