A gold-coated array of flow-through inverse pyramids applicable as substrate for entrapment and immobilization of micro-objects and for surface enhanced Raman spectroscopic measurements was fabricated using bulk micromachining techniques from silicon. Surface morphology, optical reflectance, immobilization properties, and surface enhanced Raman amplification of the array were modelled and characterized. It was found that the special perforated periodic 3D structure can be used for parallel particle and cell trapping and highly sensitive molecular analysis of the immobilized objects.

The middle Anisian extensional tectonics of the Neotethyan realm developed a small, isolated carbonate platform in the middle part of the Balaton Highland (western Hungary), resulted in the deposition of uranium-bearing seamount phosphorite on the top of the drowned platform and produced some epigenetic fluorite veins in the Middle Triassic sequence. The stable C-O isotope data of carbonates are shifted from the typical Triassic carbonate ranges, confirming the epigenetic-hydrothermal origin of veining. Primary fluid inclusions in fluorite indicate that these veins were formed from low temperature (85–169 °C) and high salinity NaCl + CaCl₂ + H₂O type (apparent total salinity: 15.91–22.46 NaCl wt%) hydrothermal fluids, similar to parent fluids of the Alpine-type Pb-Zn deposits. These findings indicate that the Triassic regional fluid circulation systems in the Alpine platform carbonates also affected the area of the Balaton Highland. This is also in agreement with the previously established palinspatic tectonic reconstructions indicating that the Triassic carbonate and basement units in the Balaton Highland area were a part of the Southern Alpine. Similar fluorite veining in phosphorite deposits is also known in the Southern Alpine areas (e.g., Monte San Giorgi, Italy). Raman spectroscopic analyses detected H₂ gas in the vapor phase of the fluid inclusions and a defect-rich fluorite structure in violet to black colored growth zones. This unique phenomenon is assumed to be the result of interaction between the uranium-rich phosphorite and the parent fluids of the epigenetic fluorite veins.