Chanan Shaul

Dr. Chanan Shaul

orcid

Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 December 2012 in Ultrasound in Obstetrics & Gynecology
Verified
Journal Article
Open access
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GLG. Liberty
G. Liberty
RBR. Boldes
R. Boldes
OSO. Shen
O. Shen
CSChanan Shaul
Chanan Shaul
SCS. M. Cohen
S. M. Cohen
SYSimcha Yagel
Simcha Yagel
Objectives: To present a systematic approach for evaluating the fetal pharynx and larynx based on two‐ and three‐dimensional ultrasound (2D‐US and 3D‐US) modalities, describing the sonographic appearance and function of the fetal upper respiratory tract and measuring the anatomical components of the pharynx and larynx.Methods: Gravidae presenting from the late first trimester to mid‐gestation for routine booked examinations with structurally normal singleton fetuses of confirmed gestational age were enrolled. Transabdominal 2D‐US was performed for anatomical and functional evaluation of the pharynx and larynx. Color Doppler was used to show fluid motion in the target area. 3D‐US (Voluson® E6 with RAB‐4‐8‐D transducer) scans of the fetal neck were acquired during fetal quiescence and in the absence of movements of the pharynx and larynx. Multiplanar reconstruction (MPR) in post‐processing allowed adjustment of the volume to obtain the coronal plane. After a learning period to understand the sonographic anatomy of the target area, we measured the pharynx width and height, the upper, middle and lower larynx width and the larynx height. Render mode was applied for spatial evaluation of the target area. We developed a new methodological approach for structured evaluation of the fetal pharynx and larynx based on five spatial planes: posterior and anterior coronal planes and high, mid and low axial planes.Results: We examined 582 fetuses during the second trimester of pregnancy; target anatomy was imaged successfully in 218 patients at 11–24 gestational weeks. Acquisition added approximately 1 min to examination time. Rates of successful visualization and measurements increased significantly as pregnancy progressed, being 23% (46/194) at 11–13 weeks, 29% (69/240) at 14–16 weeks, 35% (18/51) at 17–19 weeks and 88% (85/97) at 20–24 weeks (P < 0.01). Pharynx components identified were: the sphenoid bone, pterygoid processes, constrictor muscles, piriform recesses and uvula. Larynx components identified were: the epiglottis, aryepiglottic folds, corniculate cartilages, arytenoid cartilages, cricoid cartilage, thyroid cartilage and vocal cords. MPR showed the biconcave shape of the uvula, which may explain the ‘equals sign’ observed on 2D‐US. We observed the bilateral mode of movements of the constrictor muscles, aryepiglottic folds and vocal cords, and the bidirectional fluid jet flows through the larynx. Scatterplots of measured structures vs gestational age were created. Pharynx width ranged from 0.11 to 0.93 (mean ± SD, 0.48 ± 0.17) cm; pharynx height ranged from 0.23 to 2.01 (mean ± SD, 0.94 ± 0.34) cm; upper larynx width ranged from 0.04 to 0.37 (mean ± SD, 0.15 ± 0.07) cm; middle larynx width ranged from 0.08 to 0.77 (mean ± SD, 0.34 ± 0.16) cm; lower larynx width ranged from 0.05 to 0.64 (mean ± SD, 0.24 ± 0.11) cm; and larynx height ranged from 0.20 to 1.83 (mean ± SD, 0.71 ± 0.31) cm. All measurements were positively correlated with gestational age.Conclusions: The fetal larynx and pharynx can be evaluated thoroughly using 2D‐ and 3D‐US modalities. Knowledge of normal anatomy, function and biometry may prove useful in the evaluation of anatomical or functional pathology involving the fetal upper respiratory tract. Recognition of anatomical anomalies may enhance fetal intervention such as balloon placement in cases of diaphragmatic hernia. Copyright © 2012 ISUOG. Published by John Wiley & Sons Ltd.

14 April 2023 in Frontiers in Neurology
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Journal Article
Open access
ICItay Chen
Itay Chen
SEShalom Eligal
Shalom Eligal
OMOri Menahem
Ori Menahem
RSRiki Salem
Riki Salem
JSJean-Yves Sichel
Jean-Yves Sichel
CSChanan Shaul
Chanan Shaul
Introduction: The widely accepted treatment for sudden sensorineural hearing loss (SSNHL) is corticosteroid treatment (oral or intratympanic). The main goal of this work is to define the significance of the time between symptom onset and treatment initiation, as well as other prognostic factors, for hearing improvement.Methods: This retrospective study included 666 patients treated for SSNHL. Demographic data, audiometry, treatment method, time since symptom onset, and associated symptoms were recorded for each patient. The patients were divided into five groups according to the treatment initiation time—half a week, one week, 2 weeks, 3 weeks, or 4 weeks and over—after symptom onset. The degree of improvement was assessed by comparing the audiometry at the beginning and the end of the treatment.Results: The average period of hearing loss from symptom onset to treatment initiation was 10.8 days. Significant differences were found between the groups of half a week, one week, and 2 weeks and the groups of 3 weeks and 4 weeks and over (each separately, p < 0.001). No difference was found between the half-week, one-week, and two-week groups, nor was there a difference between the three-week and four-week-and-over groups. A correlation was found between the treatment initiation time in days and the degree of improvement in hearing for both speech recognition threshold (SRT) and discrimination, R = 0.26 p < 0.001 and R = 0.17 p < 0.001, respectively. No correlation was found for gender, age of the patients, comorbidities, or associated symptoms.Conclusion: The threshold for treatment initiation time is up to 2 weeks, after which the amplitude of hearing improvement decreases significantly. The other prognostic factors measured were not found to be statistically significant predictors.

17 November 2014 in Annals of Otology, Rhinology & Laryngology
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Journal Article
Closed access
CSChanan Shaul
Chanan Shaul
BKBenjamin Koslowsky
Benjamin Koslowsky
MRMercedes Rodriguez
Mercedes Rodriguez
YSYehuda Schwarz
Yehuda Schwarz
NMNidal Muahnna
Nidal Muahnna
JSJean-Yves Sichel
Jean-Yves Sichel
The aim was to study the therapeutic management, recurrence, and need for tonsillectomy in patients who underwent needle aspiration for peritonsillar abscess (PTA). A prospective observational design study was performed. Patients hospitalized in Shaare Zedek Medical Center between the years 2004 and 2007 with a diagnosis of PTA who underwent needle aspiration obtaining pus were included. A minimum 5-year follow-up was required for all patients. Recurrences, complications, the need for a repeated surgical procedure, length of hospital admission, and tonsillectomy were the primary end points. The study included 117 patients. One hundred four patients (88.9%) improved after 1 needle aspiration without any other intervention, whereas 13 patients (11.1%) required an additional procedure. Broad spectrum antibiotics showed a statistical advantage over penicillin only, regarding need for recurrent procedure (14.7% vs 4.7%, P = .02). No short- or long-term complications were documented. Seventeen patients (14.5%) had any recurrence. Primary recurrent tonsillitis, female sex, and younger age were predictive risk factors for recurrent events of PTA (32% vs 10%, P < .01). A total of 18 patients (15.4%) eventually underwent tonsillectomy. Needle aspiration is an effective first line procedure for patients with PTA. Tonsillectomy is not necessary in most cases. In our study, young age, female sex, and recurrent tonsillitis are negative prognostic factors for recurrence. These patients should be managed accordingly. Broad spectrum antibiotics may offer additional advantages when compared to penicillin only.

30 April 2021 in Applied Sciences
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Journal Article
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OCOhad Cohen
Ohad Cohen
JSJean-Yves Sichel
Jean-Yves Sichel
CSChanan Shaul
Chanan Shaul
ICItay Chen
Itay Chen
JRJ. Thomas Roland
J. Thomas Roland
RPRonen Perez
Ronen Perez
Although malpositioning of the cochlear implant (CI) electrode array is rare in patients with normal anatomy, when occurring it may result in reduced hearing outcome. In addition to intraoperative electrophysiologic tests, imaging is an important modality to assess correct electrode array placement. The purpose of this report was to assess the incidence and describe cases in which intraoperative plain radiographs detected a malpositioned array. Intraoperative anti-Stenver’s view plain X-rays are conducted routinely in all CI surgeries in our tertiary center before awakening the patient and breaking the sterile field. Data of patients undergoing 399 CI surgeries were retrospectively analyzed. A total of 355 had normal inner ear and temporal bone anatomy. Patients with intra or extracochlear malpositioned electrode arrays demonstrated in the intraoperative X-ray were described. There were four cases of electrode array malposition out of 355 implantations with normal anatomy (1.1%): two tip fold-overs, one extracochlear placement and one partial insertion. All electrodes were reinserted immediately; repeated radiographs were normal and the patients achieved good hearing function. Intraoperative plain anti-Stenver’s view X-rays are valuable to confirm electrode array location, allowing correction before the conclusion of surgery. These radiographs are cheaper, faster, and emit much less radiation than other imaging options, making them a viable cost-effective tool in patients with normal anatomy.

1 March 2025 in European Archives of Oto-Rhino-Laryngology
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Journal Article
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MPMoriah Peyser-Rosenberg
Moriah Peyser-Rosenberg
AHAyalon Hadar
Ayalon Hadar
NSNitzan Sofer
Nitzan Sofer
JSJean-Yves Sichel
Jean-Yves Sichel
RPRonen Perez
Ronen Perez
CSChanan Shaul
Chanan Shaul

8 October 2024 in International Journal of Pediatric Otorhinolaryngology
Verified
Journal Article
Closed access
ZAZofnat Asulin
Zofnat Asulin
OCOhad Cohen
Ohad Cohen
BFBoaz Forer
Boaz Forer
JSJean-Yves Sichel
Jean-Yves Sichel
PAPierre Attal
Pierre Attal
CSChanan Shaul
Chanan Shaul