Afsin Kariper

Dr. Afsin Kariper

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Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 November 2019 in Environmental Chemistry Letters
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SKSatiye Korkmaz
Satiye Korkmaz
AKAfsin Kariper
Afsin Kariper

1 January 2020 in Journal of Non-Crystalline Solids
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SKSatiye Korkmaz
Satiye Korkmaz
AKAfsin Kariper
Afsin Kariper

10 November 2021 in Journal of Electroceramics
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SKSatiye Korkmaz
Satiye Korkmaz
AKAfsin Kariper
Afsin Kariper

27 July 2022 in Scientific Reports
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SKSatiye Korkmaz
Satiye Korkmaz
AKAfsin Kariper
Afsin Kariper
Ceren KaramanCeren Karaman
Ceren Karaman
OKOnur Karaman
Onur Karaman
In this study, the material obtained from the sonication of the double-walled carbon nanotube and ruthenium chloride was produced as an aerogel. Then, symmetrical supercapacitor devices were made using them, and their electrochemical properties were investigated. XRD and FTIR were used in the structural analysis of the aerogel, STEM in surface images, and elemental analyses in EDX. Electrochemical analysis was performed by galvanostat/potentiostat. From the cyclic voltammetry analysis, the highest specific capacitance for MWCNT/Ruthenium hydroxide aerogels was achieved as 423 F/g at 5 mV/s. On the other hand, the corresponding values calculated from the charge–discharge curves were found to be 420.3 F/g and 319.9 F/g at the current densities of 0.5 A/g and 10.0 A/g, respectively. The capacitance retention of as-synthesized aerogel was 96.38% at the end of the 5000 consecutive consecutive cyclic voltammetry cycles.

23 June 2022 in Scientific Reports
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FDFerdane Danışman-Kalındemirtaş
Ferdane Danışman-Kalındemirtaş
AKAfsin Kariper
Afsin Kariper
GEGökçe Erdemir
Gökçe Erdemir
ESEsra Sert
Esra Sert
SESerap Erdem-Kuruca
Serap Erdem-Kuruca
Carboplatin (CP), a platinum analog, is one of the most widely used chemotherapeutic agents in the treatment of colorectal cancer. Although platinum-based drugs are quite effective in anticancer treatments, their use in a wide spectrum and effective treatment possibilities are limited due to their systemic side effects and drug resistance development. In recent years, studies have focused on increasing the therapeutic efficacy of platinum-based drugs with drug delivery systems. Gelatin, a protein, obtained by the hydrolysis of collagen, is a biocompatible and biodegradable material that can be used in nano drug delivery systems. In this study, CP-loaded gelatin-based NPs (CP-NPs) were exposed to IR light in different temperatures at 30, 35, 40, 45, and 50 °C and characterized by FESEM-EDX, FTIR, UV–Vis, DLS. Accordingly, we synthesized gelatin-based CP-NPs of different sizes between 10–290 nm by exposure to IR. We found that CP-NPs-50, 16 nm nano-sized, obtained at 50 °C had the most cytotoxicity and was 2.2 times more effective than the free drug in HCT 116 colon cancer cells. Moreover, we showed that the cytotoxicity of CP-NPs-50 in normal HUVEC cells was lower. Additionally, we demonstrated that CP-NPs enhanced apoptotic activity while not developing MDR1-related resistance in colon cancer cells. In this study, for the first time drug loaded gelatin-based nanoparticles were synthesized in different sizes with a newly self-assembly method by exposing them to infrared light at different temperatures and their anticancer effects were evaluated subsequently.

1 June 2016 in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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AKAfsin Kariper
Afsin Kariper