Scientific interest in the positive aspects of aging and the development of healthy aging has increased, given the need to ensure older people well-being and quality of life. In this sense, social support and some sociodemographic variables may have a not yet entirely clear role. The main objective of this work was to analyze the predictive relationships of age, marital status, social support and subjective well-being on the general perception of the health of a group of elderly people. The participants were 137 people (77.4% women) between 61 and 91 years old (M = 73.11; SD = 6.22); 56.9% of them had a partner and 40.1% did not. The path analysis tested indicates that social support has an indirect predictive value on perceived overall health through its influence on subjective well-being. Age and life satisfaction are the most important direct predictors of perceived overall health. Conclusions highlight the need to delve into the study of explanatory factors of the general perception of the health of the elderly and promote interventions to facilitate the development of an appropriate social support network and increase the subjective well-being of this group.