Efforts have been made to enhance the surface sensitivity of the conventional surface plasmon resonance biosensor. To improve the sensitivity, a unique two‐dimensional heterostructure layer of titanium disilicide and black phosphorus layer has been deposited over the metal surface. The titanium disilicide (TiSi ₂ ) nanosheet is placed in between silver (Ag) and black phosphorus (BP) films in the Kretschmann arrangement. This biosensor executes better over a wide range of refractive index variations, including biological cell distribution in individual blood. It may become a fast method of detecting cancerous cells and the several variants of corona and other viruses that become pandemic. Using the finite element method‐based simulation technique, the sensitivity obtained as 195.4 degree/RIU, 167.6 degree/RIU, 212.4 degree/RIU, 168.4 degree/RIU, 212.4 degree/RIU, 186.6 degree/RIU, 218.6 degree/RIU, 195.4 degree/RIU, 203.6 degree/RIU, 202.6 degree/RIU 203.6 degree/RIU, and 202.6 for basal (skin cancer), basal (normal cell), HeLa (cervical cancer), MCF‐7 (breast cancer), HeLa (normal cell), Jurkat (blood cancer), Jurkat (normal cell), PCI‐2 (adrenal gland cancer), PCI‐2 (normal cell), MDA‐MB‐231 (breast cancer), MDA‐MB‐231 (normal cell), MCF‐7 (breast cancer), and MCF‐7 (normal cell), respectively, and other performance parameters such as detection accuracy, figure of merit, and full width and half maximum (FWHM) are also evaluated.

MXenes are 2D ceramic materials, especially carbides, nitrides, and carbonitrides derived from their parent ‘MAX’ phases by the etching out of ‘A’ and are famous due to their conducting, hydrophilic, biocompatible, and tunable properties. However, they are hardly stable in the outer environment, have low biodegradability, and have difficulty in drug release, etc., which are overcome by MXene/Polymer nanocomposites. The MXenes terminations on MXene transferred to the polymer after composite formation makes it more functional. With this, there is an increment in photothermal conversion efficiency for cancer therapy, higher antibacterial activity, biosensors, selectivity, bone regeneration, etc. The hydrophilic surfaces become conducting in the metallic range after the composite formation. MXenes can effectively be mixed with other materials like ceramics, metals, and polymers in the form of nanocomposites to get improved properties suitable for advanced applications. In this paper, we review different properties like electrical and mechanical, including capacitances, dielectric losses, etc., of nanocomposites more than those like Ti₃C₂T_x/polymer, Ti₃C₂/UHMWPE, MXene/PVA-KOH, Ti₃C₂T_x/PVA, etc. along with their applications mainly in energy storing and biomedical fields. Further, we have tried to enlist the MXene-based nanocomposites and compare them with conducting polymers and other nanocomposites. The performance under the NIR absorption seems more effective. The MXene-based nanocomposites are more significant in most cases than other nanocomposites for the antimicrobial agent, anticancer activity, drug delivery, bio-imaging, biosensors, micro-supercapacitors, etc. The limitations of the nanocomposites, along with possible solutions, are mentioned.