Alice Cade

Dr. Alice Cade

New Zealand College of Chiropractic
+1
orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 January 2018 in Experimental Brain Research
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Journal Article
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SCSerpil Cecen
Serpil Cecen
Imran Khan NiaziImran Khan Niazi
Imran Khan Niazi
RNRasmus Wiberg Nedergaard
Rasmus Wiberg Nedergaard
ACAlice Cade
Alice Cade
KAKathryn Allen
Kathryn Allen
KTKemal Turker
Kemal Turker

3 June 2024 in Scientific Reports
Verified
Journal Article
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ACAlice Cade
Alice Cade
Philip TurnbullPhilip Turnbull
Philip Turnbull
Accurate, and objective diagnosis of brain injury remains challenging. This study evaluated useability and reliability of computerized eye-tracker assessments (CEAs) designed to assess oculomotor function, visual attention/processing, and selective attention in recent mild traumatic brain injury (mTBI), persistent post-concussion syndrome (PPCS), and controls. Tests included egocentric localisation, fixation-stability, smooth-pursuit, saccades, Stroop, and the vestibulo-ocular reflex (VOR). Thirty-five healthy adults performed the CEA battery twice to assess useability and test–retest reliability. In separate experiments, CEA data from 55 healthy, 20 mTBI, and 40 PPCS adults were used to train a machine learning model to categorize participants into control, mTBI, or PPCS classes. Intraclass correlation coefficients demonstrated moderate (ICC > .50) to excellent (ICC > .98) reliability (p < .05) and satisfactory CEA compliance. Machine learning modelling categorizing participants into groups of control, mTBI, and PPCS performed reasonably (balanced accuracy control: 0.83, mTBI: 0.66, and PPCS: 0.76, AUC-ROC: 0.82). Key outcomes were the VOR (gaze stability), fixation (vertical error), and pursuit (total error, vertical gain, and number of saccades). The CEA battery was reliable and able to differentiate healthy, mTBI, and PPCS patients reasonably well. While promising, the diagnostic model accuracy should be improved with a larger training dataset before use in clinical environments.

6 August 2021 in Brain Sciences
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Journal Article
Open access
PDF file
ACAlice Cade
Alice Cade
KJKelly Jones
Kelly Jones
KHKelly Holt
Kelly Holt
APAbdul Moiz Penkar
Abdul Moiz Penkar
Heidi HaavikHeidi Haavik
Heidi Haavik
Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent, chronic neurodevelopmental disorder that affects oculomotor (eye movement) control. Dysfunctional oculomotor control may result in reading or educational difficulties. This randomized controlled crossover study sought to investigate the feasibility of a larger scale trial and effects of a single session of spinal manipulation on oculomotor control in children with ADHD. Thirty children participated in the study and were randomized into either control-first or spinal manipulation first groups. The results indicate that the trial was feasible. Secondary outcomes showed that there was a significant decrease in reading time after the spinal manipulation intervention compared to the control intervention. Future studies of the effects of spinal manipulation on oculomotor control in children with ADHD are suggested.

12 January 2022 in Clinical and Experimental Optometry
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Journal Article
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ACAlice Cade
Alice Cade
Philip TurnbullPhilip Turnbull
Philip Turnbull
Traumatic brain injury (TBI) refers to the alteration of typical brain function that occurs following a blow to the head. Even a mild case of traumatic brain injury (mTBI) can lead to long-term impairment, so accurate and timely detection is vital. Visual symptoms are common following mTBI, so while it may seem to fall outside their typical scope of practice, optometrists are ideally qualified to assess the visual impacts and help with the diagnosis of mTBI. Given that mTBI is challenging to objectively diagnose and has no universally accepted diagnostic criteria, clinicians can lack confidence in diagnosing mTBI, and be hesitant in becoming involved in the management of such patients. The development of easily quantifiable techniques using eye tracking as an objective diagnostic tool provides practitioners with an easier pathway into the field, assigning numerical values to parameters which are difficult to assess using conventional optometric tests. As this evolving technology becomes increasingly integrated into optometric clinical settings, the potential for it to identify deficits accurately and reliably in patients following mTBI, and to monitor both their recovery and the effectiveness of potential treatments will increase. This paper provides an overview of clinical tests, relevant to optometrists, that can uncover oculomotor, attentional, and exteroceptive deficits following a mTBI, so that an optometrist with an interest in eye tracking can play a role in the detection and monitoring of mTBI symptoms.

21 February 2018 in Journal of Chiropractic Education
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Journal Article
Closed access
ACAlice Cade
Alice Cade
MSMatthew Sherson
Matthew Sherson
KHKelly Holt
Kelly Holt
GDGraham Dobson
Graham Dobson
KPKatie Pritchard
Katie Pritchard
HHHeidi Haavik
Heidi Haavik
Objective: This study aimed to determine if a written or visual teaching aid influenced learning retention when teaching a manual motor skill. Methods: Seventy chiropractic students who had completed an upper cervical specific chiropractic technique course were evaluated for technique-specific recall before and after a review using either a visual teaching aid or a written guide. Two randomized groups reviewed original course-written guides (n = 33) or new visual teaching aids (n = 37). Repeated-measures analysis of variance and post hoc t tests compared group differences in reevaluation scores. Results: Performance of both groups improved postintervention (F[1, 68] = 182.56, p < .001). However, the visual teaching aid group improved more than the written guide group (F[1, 68] = 4.66, p = .03). The visual teaching aid group percentage score improved by 24.4% (SD ± 12.3%, p < .01); the written guide group improved by 17.7% (SD ± 13.7%; p < .01). Conclusion: The mean learning retention improved in both the visual and the written teaching guide groups, but there was greater improvement in the visual aid group. This study suggests that visual teaching aids may be more useful than written guides when students attempt to recall information related to learning a manual motor skill.

1 February 2025 in Journal of Chiropractic Education
Verified
Journal Article
Closed access
ACAlice Cade
Alice Cade
Imran Khan NiaziImran Khan Niazi
Imran Khan Niazi
EWElly Whittaker
Elly Whittaker
RMReid Midanik
Reid Midanik
KSKirk Stevens
Kirk Stevens
Objective: To compare previously recorded quality of life scores of students at the New Zealand College of Chiropractic using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) to those after New Zealand (NZ) COVID lockdowns. Methods: Previously recorded students’ SF-36 questionnaires were collected before (2019) and after (2022) the lockdowns. Student populations were independent at each time point (pre- and post-lockdown) and were compared between 2019 and 2022 using unpaired Wilcoxon tests and to similarly aged and NZ normative data. Results: Two hundred seventy-six pre-COVID (51.1% female) and 120 post-COVID (60.8% female) data sets were returned. All pre-COVID years and scores were significantly higher or comparable with reference data ( p ≤ .050). Post-COVID scores dropped below pre-COVID and reference data—with the largest drops seen in emotional wellbeing, emotional role limitations, social, and fatigue domains ( p < .05 - p < .001). Only post-COVID physical functioning was comparable with pre-COVID or reference data ( p > .050). Conclusion: This study suggests that before COVID New Zealand College of Chiropractic perceived their quality of life as the same or better than the average New Zealander or similarly aged person. After COVID, most quality of life scores dropped substantially with emotional, social, and fatigue-related domains showing the greatest decline.