Avram Calin

Mr. Avram Calin

orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2022 in Revista Romana de Medicina de Laborator
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Journal Article
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ACAvram Calin
Avram Calin
MMMarius MărușTeri
Marius MărușTeri
Background : The importance of applying the normality tests is underlined by the way of continuing the statistical protocol for numerical data within inferential statistics, respectively by the parametric or non-parametric tests that we will apply further on. Methods : To check the calculation mode, we used sets of random values and we performed the normality assessment using statistical calculation programs. We took non-Gaussian data (n = 30, n = 50, n = 100, n = 500) and Gaussian data (n = 30, n = 50, n = 100, n = 500) for which we checked the normality of the data. Data chosen for this study were most representative for each batch (n). Results : The application of normality tests to the data under study confirms that the data are non-Gaussian for the first data set. For the Gaussian data sample, the verification of normality is confirmed by the results. Conclusion : For data up to 50 subjects, it is recommended to apply the Shapiro-Wilk test, but also to apply graphical methods to confirm the accuracy of the result. If the data samples have more than 50 values, the D’Agostino & Pearson omnibus normality test should be applied and if the statistical program does not contain this test, the Shapiro-Wilk test can be applied (in the case of SPSS). Graphical methods, although they require some experience, are useful for identifying the normality of distributions with a small number of data.

24 December 2024 in Nutrients
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Journal Article
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ACAvram Calin
Avram Calin
VNVictoria Nyulas
Victoria Nyulas
DODanusia Onisor
Danusia Onisor
IGIon Mihai Georgescu
Ion Mihai Georgescu
JSJuliánna Szakács
Juliánna Szakács
FRFlorina Ruta
Florina Ruta
Introduction: A key element for a healthy lifestyle in the formative years of a young adult is a balanced, healthy, individualized diet. Aim: The aim of this study was to analyze the eating behavior and lifestyles of students at a university in Romania, as well as the extent to which the study program interferes with these factors. Methods: A retrospective study was performed, with the data being collected through an online questionnaire via the Google Forms platform; data collection for the current study was carried out in November 2024 during a student session. Results: Out of the total of 501 questionnaires collected, 416 were completed by women and 85 by men. It can be observed that 57.65% of men (49 participants) eat three meals a day compared to 53.13% of women (221 participants). The university program influenced the students’ meal schedules for 59.88% (n = 300) of participants, while 30.94% (n = 155) declared that they never have an ordered meal schedule. For 39.92% of students, the exam period has an influence on the meal schedule, including an increase the intake of sweet foods (59.88%), and some declared that they forget to eat (33.93%). Conclusions: The food and lifestyle behaviors in the studied group show health risk elements, especially an increase in tobacco consumption, a lack of regular meal schedules, and the consumption of an excess of unhealthy snacks. It was found that intensive study schedules may intensify this behavior.

Verified
Journal Article
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BBBabaDragos-Florin Baba
BabaDragos-Florin Baba
HSHoratiu Suciu
Horatiu Suciu
ACAvram Calin
Avram Calin
GMGyorgy Manuela
Gyorgy Manuela
ADAlina Danilesco
Alina Danilesco
ASAnca Ileana Sin
Anca Ileana Sin
Background: Heart transplantation represents the treatment for patients with end-stage heart failure (HF) being symptomatic despite optimal medical therapy. We investigated the role of NMR (neutrophil-to-monocyte ratio), NLR (neutrophil-to-lymphocyte ratio), NPR (neutrophil-to-platelet ratio), NWR (neutrophil-to-white cells ratio), MLR (monocyte-to-lymphocyte ratio), PLR (platelet-to-lymphocyte ratio), MWR (neutrophil-to-white cells ratio), and LWR (lymphocyte-to-white cells ratio) at the same cut-off values previously studied, to predict complications after heart transplant within 2 months after surgery. Methods: From May 2014 to January 2021, was included 38 patients in our study from the Cardiovascular and Transplant Emergency Institute of Târgu Mureș. Results: Preoperative NMR > 8.9 (OR: 70.71, 95% CI: 3.39–1473.64; p = 0.006) was a risk factor for the apparition of post-operative paroxysmal atrial fibrillation (Afib). In contrast, preoperative MWR > 0.09 (OR: 0.04, 95% CI: 0.003–0.58; p = 0.0182) represented a protective factor against AFib, but being the risk of complications of any cause (OR: 14.74, 95% CI: 1.05–206.59, p = 0.0458). Conclusion: Preoperative elevated levels of NMR were associated with the apparition of documented AFib, with high levels of MWR as a protective factor. High MWR was a risk factor in developing complications of any cause in the first 2 months after heart transplantation.

3 June 2024 in Nutrients
Verified
Journal Article
Open access
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FRFlorina Ruta
Florina Ruta
MPMirela Ioana Mirela Pribac
Mirela Ioana Mirela Pribac
MEMardale Elena
Mardale Elena
SSSara Maria Suciu
Sara Maria Suciu
MRMaior Raluca
Maior Raluca
ACAvram Calin
Avram Calin
(1) Background: Urinary tract infections (UTIs) are among otherwise healthy women represent a problem that requires additional understanding and approaches. Evidencing the link between dysbiosis and UTIs and the associated potential risk factors could lead to therapeutic approaches with increased efficiency under the conditions of reducing the risks associated with antibiotic treatments. The purpose of this study was to evaluate dysbiosis and other potential risk factors in women with a history of urinary tract infections; (2) Methods: Fecal dysbiosis tests were performed comparatively in two groups of women. The first group in-cluded women with recurrent urinary tract infections (rUTI) who had either two or more symp-tomatic episodes of UTI in the previous six months. The second group included women with spo-radic UTIs who did not have >1 UTI during a 12-month period and who did not have another UTI in the last 12 months; (3) Results: An association was shown between intestinal dysbiosis and recurrences of urinary tract infections. Increased body weight was associated with intestinal dysbiosis. Also, the lack of knowledge regarding the risk of using antibiotics and the benefits of probiotics was associated with both dysbiosis and recurrences of urinary tract infections; (4) Conclusions: Dysbiosis can have an impact on the recurrence of urinary tract infections. The risk factors for rUTI and dysbiosis in the sphere of lifestyle are potentially controllable, broadening the perspective for new approaches and changing the paradigm in the treatment of urinary tract infections.

ACAvram Calin
Avram Calin
BMBucur Oana Maria
Bucur Oana Maria
AZAncuța Zazgyva
Ancuța Zazgyva
LALaura Avram
Laura Avram
FRFlorina Ruta
Florina Ruta
Introduction: The aim of the study was to identify the consumption of vitamin and folic acid supplements before and during pregnancy in a group of post-partum women (Romanian, Hungarian, and Roma) from Mureș County, Romania, and the influence of socio-economic and behavioral factors on the consumption of vitamins. Materials and Methods: This cross-sectional questionnaire-based study included 1278 post-partum women (during the three days of hospitalization for birth), average age 29.5, registered for giving birth in the three hospitals in Mureș County, 2015–2016. Results: In our sample, 69.58% of the interviewed women did not use any vitamin and folic acid supplements before pregnancy, while 30.70% did not use vitamin supplements during pregnancy. The lack of vitamin supplementation during pregnancy was associated with the low birth weight (<2500 g) of newborns (OR = 2.4, 95% CI [1.6–3.8]) and birth at under 36 weeks of gestation (OR = 0.5, 95% CI [0.2–0.8]). Conclusion: The use of vitamin supplements, including folic acid, continues to be deficient among Romanian women before getting pregnant, as well as during their pregnancy. We observed a lack of vitamin supplementation for pregnant women even if they were influenced by risk factors. This highlights the importance of promoting the benefits of vitamin supplementation equally among all subjects.

BBBabaDragos-Florin Baba
BabaDragos-Florin Baba
HSHoratiu Suciu
Horatiu Suciu
LHLaurentiu Huma
Laurentiu Huma
ACAvram Calin
Avram Calin
ADAlina Danilesco
Alina Danilesco
ASAnca Ileana Sin
Anca Ileana Sin
Background: The platelet-to-albumin ratio (PAR), leucocyte-to-albumin ratio (LAR), neutrophil percentage-to-albumin ratio (NPAR), and monocyte-to-albumin ratio (MAR) represent easily reproducible markers, which may predict the outcomes in various diseases. Early postoperative complications might appear after heart transplantation, such as infections, diabetes mellitus type 2 (DM2), acute graft rejection, and atrial fibrillation (AFib). Objective: The aim of our study was to investigate the PAR, LAR, NPAR, and MAR values before and after heart transplantation, and the associations of the preoperative levels of these markers with the presence of postoperative complications in first two months after surgery. Methods: Our retrospective research was directed from May 2014 to January 2021, with a total number of 38 patients being included. We used cut-off values for the ratios from previously published studies, as well as our own determination of these levels by using a receiver operating characteristic (ROC) curve. Results: By ROC analysis, the optimal preoperative PAR cut-off value was 38.84 (AUC: 0.771, p = 0.0039), with 83.3% sensitivity, and 75.0% specificity. Applying a Chi square (χ2) test, PAR > 38.84 represented an independent risk factor for complications, regardless of cause, and postoperative infections. Conclusions: Preoperative PAR > 38.84 was a risk factor of developing complications of any cause, and postoperative infections in the first two months after heart transplantation.